9-Chloro-2,3-dimethoxy-6-nitroacridine CAS 6628-92-8
| CAS No. | 6628-92-8 |
| Molecular Formula | C22H27NO2 |
| Molecular Weight | 337.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 9-Chloro-2,3-dimethoxy-6-nitroacridine.
9-Chloro-2,3-dimethoxy-6-nitroacridine (CAS 6628-92-8), molecular formula C22H27NO2 and molecular weight 337.46 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, 9-Chloro-2,3-dimethoxy-6-nitroacridine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 337.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H27NO2 |
| Molecular Weight | 337.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-2-iodo-6-(trifluoromethoxy)aniline (CAS 1000802-17-4)
- 3-Chloro-2-iodo-4-(trifluoromethoxy)aniline (CAS 1792885-92-7)
- 2-Chloro-6-iodo-4-(trifluoromethoxy)aniline (CAS 1805237-24-4)
- 5-Chloro-2-iodo-4-(trifluoromethoxy)aniline (CAS 1807189-26-9)
- 2-(5-Chloro-3-iodo-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 918485-05-9)
- 7-Chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid (CAS 2387601-50-3)
- 4-Chloro-7-fluoro-3-iodo-6-methoxyquinoline (CAS 1602859-53-9)
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Recommended Standards
- 4-[4-(azepane-1-sulfonyl)phenyl]-1,3-thiazol-2-amine (CAS 876706-39-7)
- Benzydamine Impurity 2 (CAS 47448-66-8)
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- Danazol Impurity 5 (CAS 875218-97-6)
- 3-(5-Bromothiophen-2-yl)-4-((tert-butoxycarbonyl)amino)butanoic acid (CAS 2137845-67-9)
- N-(Adamantan-1-yl)-3-oxa-8-azabicyclo[3.2.1]octane-8-carboxamide (CAS 1396708-78-3)
- (R)-2-Methyl-piperidine x HCl, 98% (CAS 155106-16-4)
- 4-Cbz-piperazine-2-carboxylic Acid (CAS 64172-98-1)
- Pomalidomide Impurity 31 (CAS 610-27-5)
- Furan-2,3,5-tricarbaldehyde (CAS 1008130-51-5)
- 7-Chloro-1H-indole-5-carbonitrile (CAS 887593-92-2)
- 1-(4-Fluorophenyl)-2-(methylamino)ethanone (CAS 766473-59-0)
- 4-Bromomethyl-2-methoxy-6-methylpyridine (CAS 1227577-71-0)
- 3AEEA-Semaglutide(Endo-AEEA-Semaglutide) (CAS CATO-C4X-2226265)
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