Lapatinib Impurity 34 CAS 1807733-95-4
| CAS No. | 1807733-95-4 |
| Molecular Formula | C29H24ClFN4O4S |
| Molecular Weight | 579.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lapatinib Impurity 34.
Lapatinib Impurity 34 (CAS 1807733-95-4) is a certified pharmaceutical impurity reference standard with the molecular formula C29H24ClFN4O4S and a molecular weight of 579.04 g/mol.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Lapatinib Impurity 34 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 579.04 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Lapatinib Impurity 34 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C29H24ClFN4O4S |
| Molecular Weight | 579.04 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Lapatinib Standards
- Lapatinib Impurity 35 (CAS 1227853-06-6)
- Lapatinib 2-Fluoro Impurity (CAS 1393112-45-2)
- Lapatinib (CAS 231277-92-2)
- Lapatinib Impurity 20 (CAS 1026818-86-9)
- Lapatinib-d4 (CAS 1184264-15-0)
- Lapatinib Impurity 16 (CAS 231277-91-1)
- Lapatinib Impurity 22 (CAS 1360431-86-2)
- Lapatinib impurity 36 (CAS CATO-C4X-119136)
Recommended Standards
- Upacicalcet Sodium Impurity 6 (CAS CATO-C4X-33926)
- Methylenebisstearamide (CAS 109-23-9)
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- Afatinib Impurity 67 (CAS CATO-C4X-100667)
- Atrasentan Impurity 17 (CAS 1140616-98-3)
- Cefminox Sodium Impurity 10 (CAS CATO-C4X-192610)
- Imatinib Impurity 19 (CAS CATO-C4X-106819)
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- N-(5-Methoxy-3-(methylthio)pyridin-2-yl)pivalamide (CAS 2794196-63-5)
- N’-hydroxy-2-methoxypyridine-4-carboximidamide (CAS 1955564-48-3)
- (D-Tyr1,N-Me-Phe3)-Neuropeptide FF (H-4752.0001) (CAS 145274-93-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com