Lapatinib CAS 231277-92-2
| CAS No. | 231277-92-2 |
| Molecular Formula | C29H26ClFN4O4S |
| Molecular Weight | 581.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Lapatinib (CAS 231277-92-2), a certified reference material (molecular formula C29H26ClFN4O4S, MW 581.06 g/mol) for analytical method development and quality control.
Lapatinib (C29H26ClFN4O4S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Lapatinib under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C29H26ClFN4O4S |
| Molecular Weight | 581.06 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2023 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Lapatinib Standards
- Lapatinib 2-Fluoro Impurity (CAS 1393112-45-2)
- Lapatinib Impurity 20 (CAS 1026818-86-9)
- Lapatinib Impurity 34 (CAS 1807733-95-4)
- Lapatinib Impurity 35 (CAS 1227853-06-6)
- Lapatinib-d4 (CAS 1184264-15-0)
- Lapatinib Impurity 22 (CAS 1360431-86-2)
- Lapatinib Impurity 16 (CAS 231277-91-1)
- Lapatinib impurity 36 (CAS CATO-C4X-119136)
Recommended Standards
- Lifitegrast Impurity 17 (CAS 2322380-15-2)
- Mometasone Furoate EP Impurity R (CAS 1370190-08-1)
- Lifitegrast Impurity 16 (CAS 2322380-18-5)
- Pemafibrate Impurity 92 (CAS CATO-C4X-290392)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com