(1R,3r)-3-(3-fluoro-4-methoxyphenyl)cyclobutan-1-amine hydrochloride CAS 1807939-97-4
| CAS No. | 1807939-97-4 |
| Molecular Formula | C11H14FNO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (1R,3r)-3-(3-fluoro-4-methoxyphenyl)cyclobutan-1-amine hydrochloride (C11H14FNOHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
(1R,3r)-3-(3-fluoro-4-methoxyphenyl)cyclobutan-1-amine hydrochloride (CAS 1807939-97-4) is a high-purity analytical reference standard with the molecular formula C11H14FNOHCl and a molecular weight of 231.69 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (1R,3r)-3-(3-fluoro-4-methoxyphenyl)cyclobutan-1-amine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H14FNO HCl |
| Molecular Weight | 231.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 3,5-Diethoxybenzaldehyde (CAS 120355-79-5)
- (3-Bromo-1-cyclopropyl-1H-pyrazol-5-yl)dimethylphosphine oxide (CAS 2903427-85-8)
- 2-(2,6-Dichlorophenyl)-2,3-dihydro-3-hydroxypyrrolo[3,4-c]pyridin-1-one (CAS 1337881-94-3)
- 2,4-Bis(hydroxymethyl)pentane-1,5-diol (CAS 6221-56-3)
- 8-Nitro-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 139605-33-7)
- (2S)-5-Oxo-2-pyrrolidinecarbothioic Acid S-Ethyl Ester (CAS 1298024-11-9)
- 7-Bromo-4-methoxythieno[3,2-d]pyrimidine (CAS 872190-91-5)
- (o-Nitrophenyl)-p-benzoquinone (CAS 105946-79-0)
- 3-Chloro-3'-(pyrrolidin-1-ylsulfonyl)-[1,1'-biphenyl]-2-carboxylic acid (CAS 1261941-08-5)
- Semaglutide impurity 258 (CAS CATO-C4X-2226258)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com