3-(5-chloro-1H-indol-1-yl)propanoic acid CAS 18108-89-9
| CAS No. | 18108-89-9 |
| Molecular Formula | C11H10ClNO2 |
| Molecular Weight | 223.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(5-chloro-1H-indol-1-yl)propanoic acid.
3-(5-chloro-1H-indol-1-yl)propanoic acid (CAS 18108-89-9) is a high-purity analytical reference standard with the molecular formula C11H10ClNO2 and a molecular weight of 223.66 g/mol.
The molecular framework of 3-(5-chloro-1H-indol-1-yl)propanoic acid (C11H10ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(5-chloro-1H-indol-1-yl)propanoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10ClNO2 |
| Molecular Weight | 223.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related chloro Standards
- 6-Chloro-2-(3,5-dimethyl-1h-pyrazol-1-yl)pyrimidin-4-amine (CAS 1014720-95-6)
- 3-(6-Chloro-1H-indol-3-yl)propanoic acid (CAS 1018612-14-0)
- 2-Chloro-4-(2-oxopyrrolidin-1-yl)benzaldehyde (CAS 1024204-74-7)
- 4-Chloro-2-(3-ethyl-1,2,4-oxadiazol-5-yl)aniline (CAS 1040345-45-6)
- Ethyl 6-chloro-1H-indole-5-carboxylate (CAS 1057076-52-4)
- Ethyl 4-chloro-1H-indole-5-carboxylate (CAS 1057076-56-8)
- Methyl 7-chloro-2-methyl-1H-indole-3-carboxylate (CAS 1082470-30-1)
- Methyl 4-chloro-2-methyl-1H-indole-3-carboxylate (CAS 1082470-33-4)
Recommended Standards
- 3-(4-Chloro-1H-indol-1-yl)propanoic acid (CAS 18108-88-8)
- (1-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclopropyl)methanol (CAS 1822785-77-2)
- 2-Chloro-1-(2-ethylbenzo[d]oxazol-4-yl)ethanone (CAS 1806300-31-1)
- 5-Chloro-2-methyl-1H-indole-3-acetic Acid (CAS 19017-52-8)
- 1-(2-Bromophenyl)-2-(trifluoromethoxy)ethan-1-amine (CAS 1334147-62-4)
- [(5-bromofuran-2-yl)methyl](methyl)amine (CAS 889943-39-9)
- 1-Benzyl-2,6-dimethyl-1H-indole-3-carbaldehyde (CAS 1134334-42-1)
- 2-Methyl-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid (CAS 933752-35-3)
- 2-((8-Bromo-2,3,4,5-tetrahydrobenzo[b]oxepin-5-yl)oxy)ethan-1-ol (CAS 2091203-48-2)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(p-tolyl)thiazol-4-yl)boronate (CAS 2223044-52-6)
- tert-Butyl (S)-2-(2-(trifluoromethoxy)phenyl)piperazine-1-carboxylate (CAS 1260603-27-7)
- Garciniaxanthone E (CAS 173294-74-1)
- 1-(3-Pyridinyl)-4-piperidinecarboxylic acid (CAS 330985-24-5)
- Semaglutide impurity 30 (CAS CATO-C4X-222630)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com