(1-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclopropyl)methanol CAS 1822785-77-2
| CAS No. | 1822785-77-2 |
| Molecular Formula | C10H10ClN3O |
| Molecular Weight | 223.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
(1-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclopropyl)methanol (CAS 1822785-77-2) is a high-purity analytical reference standard with the molecular formula C10H10ClN3O and a molecular weight of 223.66 g/mol.
The molecular framework of (1-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclopropyl)methanol (C10H10ClN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10ClN3O |
| Molecular Weight | 223.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 6-Chloro-2-(3,5-dimethyl-1h-pyrazol-1-yl)pyrimidin-4-amine (CAS 1014720-95-6)
- 3-(6-Chloro-1H-indol-3-yl)propanoic acid (CAS 1018612-14-0)
- 2-Chloro-4-(2-oxopyrrolidin-1-yl)benzaldehyde (CAS 1024204-74-7)
- 4-Chloro-2-(3-ethyl-1,2,4-oxadiazol-5-yl)aniline (CAS 1040345-45-6)
- Ethyl 6-chloro-1H-indole-5-carboxylate (CAS 1057076-52-4)
- Ethyl 4-chloro-1H-indole-5-carboxylate (CAS 1057076-56-8)
- Methyl 7-chloro-2-methyl-1H-indole-3-carboxylate (CAS 1082470-30-1)
- Methyl 4-chloro-2-methyl-1H-indole-3-carboxylate (CAS 1082470-33-4)
Recommended Standards
- 3-(5-chloro-1H-indol-1-yl)propanoic acid (CAS 18108-89-9)
- 5-Chloro-2-methyl-1H-indole-3-acetic Acid (CAS 19017-52-8)
- 3-(4-Chloro-1H-indol-1-yl)propanoic acid (CAS 18108-88-8)
- Methyl 4-Chloroindole-3-acetate (CAS 19077-78-2)
- N-((3-chloropyridin-4-yl)methyl)-2,2,2-trifluoroethan-1-amine (CAS 1491425-88-7)
- (10-(Naphthalen-1-yl)anthracen-9-yl)boronic acid (CAS 400607-46-7)
- 5,7-Dimethyl-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonyl chloride (CAS 112729-27-8)
- 4,7-Di-O-methylnaringenin (CAS 29424-96-2)
- 3-Methoxy-6-phenyl-1,2,4-triazin-5(4H)-one (CAS 37526-36-6)
- 2-Phenylpyrimidine-5-carbaldehyde (CAS 130161-46-5)
- N-(benzo[d]thiazol-2-yl)-3-oxobutanamide (CAS 4692-94-8)
- (2S,5S)-1-tert-Butyl 2-methyl 5-phenylpyrrolidine-1,2-dicarboxylate (CAS 1552271-23-4)
- 2-Cyano-N'-[(2E)-4-oxo-4-phenylbutan-2-ylidene]acetohydrazide (CAS 1086229-94-8)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788677)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com