8-Chloro-6-hydroxyquinoline CAS 18119-24-9
| CAS No. | 18119-24-9 |
| Molecular Formula | C9H6ClNO |
| Molecular Weight | 179.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 179.60 g/mol gives 8-Chloro-6-hydroxyquinoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
8-Chloro-6-hydroxyquinoline (CAS 18119-24-9), molecular formula C9H6ClNO and molecular weight 179.60 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C9H6ClNO, 8-Chloro-6-hydroxyquinoline contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 179.60 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-Chloro-6-hydroxyquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H6ClNO |
| Molecular Weight | 179.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-chloro-5-hydroxy-pyridine-2-carboxylic acid (CAS 1060804-56-9)
- 3-Chloro-1H-indole-2-carbaldehyde (CAS 110912-15-7)
- 3-Chloro-1H-indole-4-carbaldehyde (CAS 1216113-27-7)
- 5-Chloro-3-methyleneisoindolin-1-one (CAS 1239331-77-1)
- 4-Chloro-5-phenyloxazole (CAS 1240617-68-8)
- 2-Chloro-4-formyl-3-methylbenzonitrile (CAS 1297544-91-2)
- 1-Chloro-8-hydroxyisoquinoline (CAS 1374651-67-8)
- 3-Chloro-5-hydroxyisoquinoline (CAS 1374652-47-7)
Recommended Standards
- 6-Chloroquinolin-2(1H)-one (CAS 1810-67-9)
- 4-Chloro-7-hydroxyquinoline (CAS 181950-57-2)
- 2-(3-chloro-1H-1,2,4-triazol-1-yl)propanoic acid (CAS 1798730-56-9)
- 5-Chloroisoquinolin-3(2H)-one (CAS 1822888-01-6)
- Nitroxoline-d4 (CAS 4008-48-4(unlabeled))
- Azvudine hydrochloride (CAS 1333126-31-0)
- Ethyl 6-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate (CAS 134388-85-5)
- Ethyl 4-(1-((tert-butoxycarbonyl)amino)cyclopropyl)pyrrolidine-3-carboxylate (CAS 1373028-31-9)
- tert-butyl carbamothioylformate (CAS 16721-41-8)
- Ethyl 4-cyano-2,6-difluorobenzoate (CAS 1807048-08-3)
- Decanoic Acid (CAS 334-48-5)
- (1-Methyl-3-phenyl-1h-pyrazol-5-yl)methanol (CAS 864068-97-3)
- 1-Ethylcyclopropanamine (CAS 785754-29-2)
- Cholecystokinin Octapeptide (desulfated) (H-2070.0005) (CAS 198483-36-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com