(E)-3-Chloro-2,3-bis(4-methoxyphenyl)acrylaldehyde CAS 181308-92-9
| CAS No. | 181308-92-9 |
| Molecular Formula | C17H15ClO3 |
| Molecular Weight | 302.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (E)-3-Chloro-2,3-bis(4-methoxyphenyl)acrylaldehyde is closely related to a steroid core, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(E)-3-Chloro-2,3-bis(4-methoxyphenyl)acrylaldehyde (CAS 181308-92-9), molecular formula C17H15ClO3 and molecular weight 302.75 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (E)-3-Chloro-2,3-bis(4-methoxyphenyl)acrylaldehyde (C17H15ClO3) contains a steroid core, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 302.75 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H15ClO3 |
| Molecular Weight | 302.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
| Halogen Content | Cl-containing |
Related E Standards
- (E)-3-(3-chloro-4-methoxyphenyl)-1-(3-methoxyphenyl)prop-2-en-1-one (CAS 861207-60-5)
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- 6-Benzyl-4-chloro-9-methyl-5,6,8,9-tetrahydro-7H-pyrimido[4,5-e][1,4]diazepin-7-one (CAS 1228425-29-3)
- 2-Chloro-1-[5-(furan-2-yl)-3-(4-methylphenyl)-4,5-dihydro-1h-pyrazol-1-yl]ethan-1-one (CAS 625109-32-2)
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- 3-Chloro-8H-quinolino[4,3,2-kl]acridine (CAS 198025-90-0)
- 5-Chloro-2-(2-(dimethylamino)ethyl)-2H-benzo[f]isoindole-4,9-dione (CAS 89479-37-8)
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Recommended Standards
- (2E)-1-(3-Chlorophenyl)-3-(2,3-dimethoxyphenyl)prop-2-en-1-one (CAS 1801666-51-2)
- (2E)-1-(2-Chlorophenyl)-3-(2,4-dimethoxyphenyl)prop-2-en-1-one (CAS 205176-71-2)
- Glafenic Acid-d4 (CAS 1794964-36-5)
- (2E)-1-(2-Chlorophenyl)-3-(2,5-dimethoxyphenyl)prop-2-en-1-one (CAS 219298-69-8)
- 2-(4-Methylphenyl)cyclohexan-1-one (CAS 52776-14-4)
- 2,2-Dimethylpropyl 2-pyridyl ketone (CAS 138835-86-6)
- Tert-butyl (R)-5-amino-7,7-difluoro-2-azaspiro[3.4]Octane-2-carboxylate (CAS 2306250-07-5)
- Ethyl 2,4-dioxo-3-phenyl-3-azabicyclo[3.1.0]Hexane-6-carboxylate (CAS 3120-09-0)
- 2-(2,6-dioxo-3-piperidyl)-N-(2-hydroxypropyl)-1-oxo-isoindoline-5-carboxamide (CAS 2390681-68-0)
- tert-Butyl 1-cyclobutylpyrrolidin-3-ylcarbamate (CAS 1336912-71-0)
- N-(4-Methoxybenzo[d]thiazol-2-yl)-1-methyl-1H-pyrazole-3-carboxamide (CAS 1020489-07-9)
- 2-Amino-6-methyl-3-nitropyridine (CAS 21901-29-1)
- 5-(Chloromethyl)-2-(4-(trifluoromethoxy)phenyl)pyridine (CAS 851069-98-2)
- Liraglutide (CAS 204656-20-2)
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