Carbidopa EP Impurity B CAS 18181-08-3

Description

Compared with other compounds in its class, the molecular weight of 225.24 g/mol gives Carbidopa EP Impurity B distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Carbidopa EP Impurity B (CAS 18181-08-3), a pharmacopoeial impurity reference standard (molecular formula C11H15NO4, MW 225.24 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Carbidopa EP Impurity B (C11H15NO4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Carbidopa EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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