3-Fluoro-4-(1h-1,2,4-triazol-1-yl)aniline CAS 181997-13-7
| CAS No. | 181997-13-7 |
| Molecular Formula | C8H7FN4 |
| Molecular Weight | 178.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-Fluoro-4-(1h-1,2,4-triazol-1-yl)aniline (CAS 181997-13-7), a certified reference material (molecular formula C8H7FN4, MW 178.17 g/mol) for analytical method development and quality control.
The molecular framework of 3-Fluoro-4-(1h-1,2,4-triazol-1-yl)aniline (C8H7FN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7FN4 |
| Molecular Weight | 178.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Fluoro Standards
- 6-Fluoro-4-hydrazono-3,4-dihydroquinazoline (CAS 1019166-35-8)
- 5-(4-fluoro-3-methylphenyl)-1H-1,2,3,4-tetrazole (CAS 1020969-35-0)
- 2-Fluoro-5-(4H-1,2,4-triazol-4-yl)aniline (CAS 1082766-13-9)
- 2-Fluoro-6-(1h-1,2,4-triazol-1-yl)aniline (CAS 1183856-70-3)
- 6-Fluoro-imidazo[1,2-a]pyridine-3-carboxamidine (CAS 1220039-94-0)
- 2-Fluoro-5-(1h-1,2,4-triazol-3-yl)aniline (CAS 1247084-34-9)
- 3-fluoro-2-(1H-1,2,4-triazol-3-yl)aniline (CAS 1249534-87-9)
- 5-(5-Fluoro-2-methylphenyl)-2H-tetrazole (CAS 1250242-44-4)
Recommended Standards
- 3-Fluoro-4-(4H-1,2,4-triazol-3-yl)aniline (CAS 1694451-72-3)
- 1-(4-Fluorophenyl)-1H-1,2,4-triazol-3-amine (CAS 1858445-20-1)
- 5-Amino-3-(4-fluorophenyl)-1H-1,2,4-triazole (CAS 168893-35-4)
- (2,4,5-Trifluorophenyl)methanethiol (CAS 886498-39-1)
- Tert-butyl 3-bromo-1H-pyrazolo[4,3-c]pyridine-1-carboxylate (CAS 1286753-97-6)
- 4-(3-Bromopropyl)-1,2-dichlorobenzene (CAS 29648-26-8)
- 2-(4-(Azepan-1-ylsulfonyl)phenyl)-5-(4-methylpiperidin-1-yl)oxazole-4-carbonitrile (CAS 940999-04-2)
- N-(4-chloro-2-methylphenyl)-2-hydrazinyl-2-oxoacetamide (CAS 1211487-29-4)
- 1-(4-Chlorophenethyl)piperazine (CAS 55455-93-1)
- 1-((9h-Purin-6-yl)thio)butan-2-one (CAS 159627-84-6)
- 3-(Phenylthio)-1-(4-(pyrazin-2-yloxy)piperidin-1-yl)propan-1-one (CAS 1421482-30-5)
- 1-(3-Isopropyl-1H-pyrazol-1-yl)propan-2-ol (CAS 742096-95-3)
- 5-(Pentan-2-yl)isoxazol-3-amine (CAS 1480843-46-6)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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