Methyl 1H-pyrazole-4-carboxylate hydrochloride CAS 181997-36-4
| CAS No. | 181997-36-4 |
| Molecular Formula | C5H6N2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Methyl 1H-pyrazole-4-carboxylate hydrochloride (CAS 181997-36-4), molecular formula C5H6N2O2HCl and molecular weight 162.57 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 1H-pyrazole-4-carboxylate hydrochloride (C5H6N2O2HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H6N2O2 HCl |
| Molecular Weight | 162.57 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2008 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Methyl 3-Hydroxycyclohexanecarboxylate (CAS 37722-82-0)
- 5-Chloro-2-methyl-2,3-dihydroisothiazole (CAS 87701-39-1)
- N-Hydroxy-1-benzofuran-5-carboximidamide (CAS 1307231-09-9)
- 2-Bromo-5-phenyl-5H-benzo[b]carbazole (CAS 1268271-78-8)
- 4-Oxo-8-(trifluoromethoxy)-1,4-dihydroquinoline-3-carboxylic acid (CAS 40516-40-3)
- (Z)-Hex-3-enedinitrile (CAS 28317-02-4)
- 2-Chloro-N-(2-oxo-2-(pyrazin-2-yl)ethyl)acetamide (CAS 1353980-95-6)
- Nortriptyline EP Impurity B (CAS 303-50-4)
- 1-(6-Chloro-5-(trifluoromethyl)pyridin-3-yl)ethanone (CAS 1245915-41-6)
- Des-[Gly]31-Semaglutide(x TFA Salt) (CAS 873874-39-6(free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com