Methyl 3-(3-chlorophenyl)-4-fluorobenzoate CAS 1820740-85-9
| CAS No. | 1820740-85-9 |
| Molecular Formula | C14H10ClFO2 |
| Molecular Weight | 264.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Methyl 3-(3-chlorophenyl)-4-fluorobenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Methyl 3-(3-chlorophenyl)-4-fluorobenzoate (CAS 1820740-85-9), molecular formula C14H10ClFO2 and molecular weight 264.68 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system, Methyl 3-(3-chlorophenyl)-4-fluorobenzoate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 264.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H10ClFO2 |
| Molecular Weight | 264.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
Related Methyl Standards
- Methyl 4-(2-chlorophenyl)-2-fluorobenzoate (CAS 1820603-44-8)
- Methyl 5-(2-chlorophenyl)-2-fluorobenzoate (CAS 1820607-05-3)
- Methyl 3-(2-chlorophenyl)-5-fluorobenzoate (CAS 1820674-46-1)
- Methyl 3-(3-chlorophenyl)-5-fluorobenzoate (CAS 1820674-51-8)
- Methyl 4-(4-chlorophenyl)-2-fluorobenzoate (CAS 1820705-31-4)
- Methyl 5-(3-chlorophenyl)-2-fluorobenzoate (CAS 1820740-96-2)
- Methyl 4-(3-chlorophenyl)-2-fluorobenzoate (CAS 1820741-87-4)
- (3-Chlorophenyl)(3-fluoro-4-methoxyphenyl)methanone (CAS 844885-00-3)
Recommended Standards
- Methyl 2-chloro-4-(3-fluorophenyl)benzoate (CAS 1820707-61-6)
- Methyl 2-chloro-4-(4-fluorophenyl)benzoate (CAS 1820706-24-8)
- 5-chloro-6-(2,2-difluoroethoxy)-1,3-benzothiazol-2-amine (CAS 1855906-91-0)
- Sulpiride Impurity 14 (CAS 191471-91-7)
- 7-Bromo-5-fluoro-4-methylphthalazin-1(2H)-one (CAS 2654747-55-2)
- Ethyl 7,8-dichloro-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 175134-95-9)
- 4-Isopropyl-N,N-dimethylpyridazin-3-amine (CAS 27772-42-5)
- 2-Methyl-4-nitroisoindolin-1-one (CAS 682757-52-4)
- Mn (CAS CATO-CCRM106026)
- Bromo-4,6-di-O-acetyl-α-D-mannopyranose-2,3-carbonate (CAS 53958-21-7)
- 1-Methyl-4-(propylsulfinyl)benzene (CAS 21865-09-8)
- methyl 3-(2,4-dioxohexahydropyrimidin-1-yl)-4-fluoro-benzoate (CAS 2858742-34-2)
- 1′,5′-Dihydro-1′,2′-diphenyl-2′H-[5,6]fullereno-C60-Ih-[1,9-c]pyrrole (CAS 1373934-14-5)
- Semaglutide Impurity 125 xTFA Salt (CAS CATO-C4X-2226125)
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