Methyl 5-(3-chlorophenyl)-2-fluorobenzoate CAS 1820740-96-2
| CAS No. | 1820740-96-2 |
| Molecular Formula | C14H10ClFO2 |
| Molecular Weight | 264.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 5-(3-chlorophenyl)-2-fluorobenzoate is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Methyl 5-(3-chlorophenyl)-2-fluorobenzoate (CAS 1820740-96-2), a certified reference material (molecular formula C14H10ClFO2, MW 264.68 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 5-(3-chlorophenyl)-2-fluorobenzoate (C14H10ClFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H10ClFO2 |
| Molecular Weight | 264.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
Related Methyl Standards
- Methyl 4-(2-chlorophenyl)-2-fluorobenzoate (CAS 1820603-44-8)
- Methyl 5-(2-chlorophenyl)-2-fluorobenzoate (CAS 1820607-05-3)
- Methyl 3-(2-chlorophenyl)-5-fluorobenzoate (CAS 1820674-46-1)
- Methyl 3-(3-chlorophenyl)-5-fluorobenzoate (CAS 1820674-51-8)
- Methyl 4-(4-chlorophenyl)-2-fluorobenzoate (CAS 1820705-31-4)
- Methyl 3-(3-chlorophenyl)-4-fluorobenzoate (CAS 1820740-85-9)
- Methyl 4-(3-chlorophenyl)-2-fluorobenzoate (CAS 1820741-87-4)
- (3-Chlorophenyl)(3-fluoro-4-methoxyphenyl)methanone (CAS 844885-00-3)
Recommended Standards
- Methyl 2-chloro-4-(3-fluorophenyl)benzoate (CAS 1820707-61-6)
- 5-chloro-6-(2,2-difluoroethoxy)-1,3-benzothiazol-2-amine (CAS 1855906-91-0)
- Methyl 2-chloro-4-(4-fluorophenyl)benzoate (CAS 1820706-24-8)
- Sulpiride Impurity 14 (CAS 191471-91-7)
- 4'-Hydroxy-5-methoxy-[1,1'-biphenyl]-2-carboxylic acid (CAS 1181608-93-4)
- 3-Bromobenzoic-2,4,5,6-d4 acid (CAS 81395-53-1)
- 1-(4-Benzylpiperazin-1-yl)-3-hydroxy-2-phenylpropan-1-one (CAS 1313712-45-6)
- 1-(2-Morpholinoethyl)-1H-pyrazole-4-carboxylic acid hydrochloride (CAS 1311313-83-3)
- 6-aminoquinoline-2-thiol (CAS 1154583-22-8)
- Avibactam Impurity 64 (CAS CATO-C4X-134864)
- 2-(5'-Fluoro-2'-methoxy-[1,1'-biphenyl]-3-yl)ethan-1-ol (CAS 1443342-46-8)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-acetamidopropanoic acid (CAS 181952-29-4)
- ethyl 5-amino-1-(2-fluorophenyl)-1H-imidazole-4-carboxylate (CAS 1283340-97-5)
- (Glu9)-Exenatide (2-39) trifluoroacetate salt (CAS 196109-34-9)
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