5-Bromo-1-(3-fluorobenzyl)pyrimidin-2(1h)-one CAS 1822826-57-2
| CAS No. | 1822826-57-2 |
| Molecular Formula | C11H8BrFN2O |
| Molecular Weight | 283.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Bromo-1-(3-fluorobenzyl)pyrimidin-2(1h)-one (CAS 1822826-57-2) is a high-purity analytical reference standard with the molecular formula C11H8BrFN2O and a molecular weight of 283.10 g/mol.
The molecular framework of 5-Bromo-1-(3-fluorobenzyl)pyrimidin-2(1h)-one (C11H8BrFN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Bromo-1-(3-fluorobenzyl)pyrimidin-2(1h)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8BrFN2O |
| Molecular Weight | 283.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 1-(2-(4-Bromo-1h-pyrazol-1-yl)-6-fluorophenyl)ethan-1-one (CAS 1179940-44-3)
- 7-Bromo-6-(4-fluorophenyl)-2,3-dihydropyrazolo[5,1-b]oxazole (CAS 1429893-27-5)
- 2-(4-Bromo-3-fluorophenoxy)-4-methylpyrimidine (CAS 1443981-51-8)
- 10-Bromo-9-fluoro-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine (CAS 1451084-92-6)
- 6-Bromo-2-(2-fluorobenzyl)pyridazin-3(2h)-one (CAS 1616402-77-7)
- 5-Bromo-2-((4-fluorobenzyl)oxy)pyrimidine (CAS 1635413-26-1)
- 5-Bromo-2-((3-fluorobenzyl)oxy)pyrimidine (CAS 1635413-27-2)
- 6-Bromo-2-(3-fluorobenzyl)pyridazin-3(2h)-one (CAS 1822826-95-8)
Recommended Standards
- (3-Fluoro-4-(2-(4-hydroxypiperidin-1-yl)ethoxy)phenyl)boronic acid (CAS 1704064-11-8)
- 6-Bromo-2-cyclopropyl-8-fluoroquinazolin-4(3H)-one (CAS 1849606-37-6)
- (3-fluoro-4-(3-morpholinopropoxy)phenyl)boronic acid (CAS 944279-32-7)
- 2-Bromo-5-((3-fluorobenzyl)oxy)pyrazine (CAS 2090011-26-8)
- Desamino Chloro (R)-Fluoxetine (CAS 1346617-29-5)
- 3-fluoro-5-hydroxy-4,7-dimethyl-chromen-2-one (CAS 2920243-35-0)
- 5-Fluoro-2-(methylthio)benzo[d]thiazole (CAS 874880-53-2)
- Naltrexone Hydrochloride (CAS 16676-29-2)
- 2-Amino-1-(pyridin-3-yl)ethanone hydrochloride (CAS 93103-00-5)
- 2-(4-Ethyl-2,3-dioxopiperazin-1-yl)-N-(4-fluorobenzyl)acetamide (CAS 868965-08-6)
- 2-Methyl-4-(pyrrolidin-1-yl)quinazolin-7-ol (CAS 646450-53-5)
- Ethyl 7-fluoro-3-methyl-1H-indole-2-carboxylate (CAS 866211-11-2)
- 7-Fluoro-1,2,3,4-tetrahydro-1,5-naphthyridine (CAS 1211527-95-5)
- Peptide Impurity 24 (CAS CATO-CPTD788824)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com