Naltrexone Hydrochloride CAS 16676-29-2
| CAS No. | 16676-29-2 |
| Molecular Formula | C20H23NO4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Naltrexone Hydrochloride (CAS 16676-29-2) is a high-purity analytical reference standard with the molecular formula C20H23NO4HCl and a molecular weight of 377.86 g/mol.
The molecular framework of Naltrexone Hydrochloride (C20H23NO4HCl) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Naltrexone Hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H23NO4 HCl |
| Molecular Weight | 377.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Naltrexone Standards
- Naltrexone EP Impurity A (CAS 1007856-83-8)
- Naltrexone Impurity 23 (CAS 102272-79-7)
- Naltrexone Impurity 15 (CAS 111129-14-7)
- Naltrexone impurity 30 (CAS 112242-13-4)
- Naltrexone Impurity 19 (CAS 112269-62-2)
- Naltrexone Impurity 13 (CAS 1201-90-7)
- Naltrexone Impurity 11 (CAS 123086-68-0)
- Naltrexone-D3 (CAS 1261080-26-5)
Recommended Standards
- N4-(1-Benzyl-1H-indazol-5-yl)-N6,N6-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine (CAS 202272-68-2)
- 4-(Aminomethyl)-5-(difluoromethyl)-3-methylpyridin-2-amine (CAS 1806922-76-8)
- N-(4-Phenoxyphenyl)-1-[6-(trifluoromethyl)pyrimidin-4-yl]piperidine-4-carboxamide (CAS 1775546-75-2)
- 3-Amino-2-fluoro-5-hydroxybenzoic Acid (CAS 1025127-39-2)
- 2-(3-(2-Fluorophenyl)-5-(trifluoromethyl)pyridin-2-yl)acetic acid (CAS 1214360-24-3)
- 1-(Trifluoromethyl)-2-oxa-6-azaspiro[3.3]heptane (CAS 1454909-15-9)
- (R)-1-(3,5-difluorophenyl)propan-1-amine (CAS 473733-16-3)
- Guanidine bromide (CAS 19244-98-5)
- 4-Chloro-1H-pyrazol-3-amine (CAS 54301-34-7)
- Semaglutide impurity 250 (CAS CATO-C4X-2226250)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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