2,2,2-Trifluoro-4’-hydroxyacetophenone CAS 1823-63-8
| CAS No. | 1823-63-8 |
| Molecular Formula | C8H5F3O2 |
| Molecular Weight | 190.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2,2,2-Trifluoro-4’-hydroxyacetophenone (CAS 1823-63-8), molecular formula C8H5F3O2 and molecular weight 190.12 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 2,2,2-Trifluoro-4’-hydroxyacetophenone is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 190.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2,2,2-Trifluoro-4’-hydroxyacetophenone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5F3O2 |
| Molecular Weight | 190.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Trifluoro Standards
- 2,4,5-Trifluoro-3-methylbenzoic Acid (CAS 112822-85-2)
- 1,1,1-Trifluoro-3-(pyrazin-2-yl)propan-2-one (CAS 116655-36-8)
- 3,4,6-Trifluoro-2-methylbenzoic Acid (CAS 119916-22-2)
- 2,4,5-Trifluoro-3-methoxybenzaldehyde (CAS 1260679-12-6)
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Recommended Standards
- 1,1-Difluoro-2-methoxy-2-oxoethane-1-sulfonic acid (CAS 18225-64-4)
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- 2,4,5-Trifluorobenzohydrazide (CAS 1824155-80-7)
- 2-Chloroimidazo[1,2-a]pyridine-3-carbonitrile (CAS 131773-48-3)
- 3-[(2-Fluorophenyl)methoxy]piperidine (CAS 1046921-94-1)
- 5,6-Dihydro-1H-imidazo[1,2-a]imidazole (CAS 67139-08-6)
- N-(2-(2-hydroxynaphthalen-1-yl)-4-methoxy-3,5-dimethylphenyl)-4-methylbenzenesulfonamide (CAS 1832514-29-0)
- Acalabrutinib Impurity 3 (CAS CATO-C4X-30553)
- 3-Cyclopropyl-4-(trifluoromethyl)isoxazolo[5,4-b]pyridin-6(7H)-one (CAS 1018047-82-9)
- 3,5-Diethoxyisonicotinaldehyde (CAS 164077-50-3)
- Fenoxaprop-P-ethyl (CAS 71283-80-2)
- N-(1-ethylpiperidin-4-yl)propionamide (CAS 1015853-29-8)
- ([D2]Gly4)-Cholecystokinin Octapeptide (sulfated) ammonium salt (CAS 1926163-74-7)
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