2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2,2-difluoroacetic acid CAS 1823183-02-3
| CAS No. | 1823183-02-3 |
| Molecular Formula | C8H3ClF5NO2 |
| Molecular Weight | 275.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2,2-difluoroacetic acid (CAS 1823183-02-3) is a high-purity analytical reference standard with the molecular formula C8H3ClF5NO2 and a molecular weight of 275.56 g/mol.
2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2,2-difluoroacetic acid (C8H3ClF5NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2,2-difluoroacetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H3ClF5NO2 |
| Molecular Weight | 275.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 6-Chloro-5-(difluoromethyl)-2-(trifluoromethyl)nicotinic acid (CAS 1804717-78-9)
- 2-Chloro-6-(difluoromethyl)-4-(trifluoromethyl)nicotinic acid (CAS 1804717-96-1)
- 2-Chloro-4-(difluoromethyl)-6-(trifluoromethyl)nicotinic acid (CAS 1805082-64-7)
- 4-Chloro-6-(difluoromethyl)-5-(trifluoromethyl)nicotinic acid (CAS 1805083-05-9)
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Recommended Standards
- 6-Chloro-3-(difluoromethyl)-5-(trifluoromethyl)picolinic acid (CAS 1807127-07-6)
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- 6-Chloro-5-(difluoromethyl)-4-(trifluoromethyl)nicotinic acid (CAS 1807126-95-9)
- 7-bromo-5-(chloromethyl)-2,2-dimethyl-2,3-dihydro-1-benzofuran (CAS 1146290-40-5)
- (2-(Morpholinomethyl)pyridin-4-yl)boronic acid (CAS 1182273-53-5)
- Pantoprazole Impurity 61 (CAS 887412-09-1)
- 3-(3,4-Dihydro-2H-quinolin-1-yl)propan-1-amine (CAS 2637-31-2)
- N-(2,5-dimethylphenyl)-2-((3-ethyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1207007-37-1)
- 4-(tert-Butoxycarbonyl)-1-(5-chloropyrimidin-2-yl)piperazine-2-carboxylic acid (CAS 1261229-66-6)
- 2-(3-methoxypyridin-2-yl)acetic acid hydrochloride (CAS 1798728-20-7)
- 3-(4-(Trifluoromethyl)phenoxy)cyclobutan-1-amine (CAS 1494547-79-3)
- Naloxone Impurity 18 (CAS 156047-22-2)
- 2-(Propylthio)benzo[d]thiazol-6-amine (CAS 64350-92-1)
- endo-Arg30-Semaglutide (CAS CATO-C4X-2226281)
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