N-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2,2-difluoroethyl}-N-nitro(methylsulfanyl)methanimidamide CAS 1823194-68-8
| CAS No. | 1823194-68-8 |
| Molecular Formula | C10H8ClF5N4O2S |
| Molecular Weight | 378.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2,2-difluoroethyl}-N-nitro(methylsulfanyl)methanimidamide.
CATO supplies N-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2,2-difluoroethyl}-N-nitro(methylsulfanyl)methanimidamide (CAS 1823194-68-8), a certified reference material (molecular formula C10H8ClF5N4O2S, MW 378.71 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2,2-difluoroethyl}-N-nitro(methylsulfanyl)methanimidamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 378.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2,2-difluoroethyl}-N-nitro(methylsulfanyl)methanimidamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8ClF5N4O2S |
| Molecular Weight | 378.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(3-Chloro-4-fluorophenyl)-N-(7-fluoro-6-nitroquinazolin-4-yl)acetamide (CAS 1632286-05-5)
- 1-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid (CAS 400075-82-3)
- 1-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-2,4-dioxohexahydropyrimidine-5-carboximidamide (CAS 341966-22-1)
- 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-1-oxo-1,2-dihydroisoquinoline-4-carbonitrile (CAS 303151-89-5)
- 4-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indol-3-yl)-1,2-dihydro-3H-pyrazol-3-one (CAS 303152-88-7)
- 4-Chloro-n-[2-(difluoromethoxy)phenyl]-3-nitrobenzene-1-sulfonamide (CAS 749920-49-8)
- 3-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-6,7,8-trifluoroquinolin-4(1H)-one (CAS 866135-60-6)
- 2-(3-Chloro-2-hydroxyphenyl)-5-hydroxy-3,7,8-trimethoxy-4H-chromen-4-one (CAS 23363-64-6)
Recommended Standards
- 1-(4-chlorophenyl)-3-[3,5-di(trifluoromethyl)phenyl]prop-2-en-1-one (CAS 254096-58-7)
- 5α-Cholestane-2,2,3,3,4,4-d6 (CAS 358731-18-7)
- 7-(4-Bromo-2,6-dimethylphenyl)-4-chloro-2,5,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 872866-00-7)
- Eldecalcitol Impurity 55 (CAS 2304823-98-9)
- (3S)-1,3-dimethylpiperazine;dihydrochloride (CAS 1152110-30-9)
- 1-Allyl-3,5-dibromo-1H-pyrazole-4-carbonitrile (CAS 2380036-95-1)
- 2-methyl-octahydro-1H-indole (CAS 50669-77-7)
- Ceranib 1 (CAS 328076-61-5)
- 5-(Methoxymethyl)pyridine-3-carboxylic acid (CAS 1000298-38-3)
- 2-[(4-Aminophenyl)thio]-N-[4-(aminosulfonyl)-phenyl]propanamide (CAS 913241-96-0)
- Potassium ferricyanide(II) trihydrate (CAS 14459-95-1)
- 5-(4-fluorophenyl)-3-(prop-2-en-1-yl)-2-sulfanyl-3H,4H-thieno[2,3-d]pyrimidin-4-one (CAS 307341-18-0)
- SR 144528 (CAS 192703-06-3)
- Semaglutide impurity 197 (CAS CATO-C4X-2226197)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com