2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-1-oxo-1,2-dihydroisoquinoline-4-carbonitrile CAS 303151-89-5
| CAS No. | 303151-89-5 |
| Molecular Formula | C17H10ClF3N4O |
| Molecular Weight | 378.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-1-oxo-1,2-dihydroisoquinoline-4-carbonitrile (C17H10ClF3N4O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-1-oxo-1,2-dihydroisoquinoline-4-carbonitrile (CAS 303151-89-5), molecular formula C17H10ClF3N4O and molecular weight 378.74 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-1-oxo-1,2-dihydroisoquinoline-4-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H10ClF3N4O |
| Molecular Weight | 378.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related chloro Standards
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Recommended Standards
- 6-Benzoyl-2-(4-chlorophenyl)-5-(trifluoromethyl)-2,3-dihydropyridazin-3-one (CAS 478032-30-3)
- 6-(3-Chlorobenzoyl)-2-phenyl-5-(trifluoromethyl)pyridazin-3(2H)-one (CAS 478043-61-7)
- Methyl 2-((4-amino-5-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)pyrimidin-2-yl)thio)acetate (CAS 1823184-37-7)
- Opicapone Impurity 55 (CAS CATO-C4X-240455)
- 4-(3-Methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)benzenesulfonamide (CAS 28093-46-1)
- 4-(Prop-2-yn-1-yl)piperidine hydrochloride (CAS 2172188-51-9)
- 5-Bromo-1,3,4-thiadiazole-2-carbaldehyde (CAS 1547015-45-1)
- Nicorandil Impurity 38 (CAS CATO-C4X-190738)
- Cinnamylamine Hydrochloride (CAS 5586-89-0)
- 2-chloro-4-methoxy-3-nitro-pyridine (CAS 6980-09-2)
- (S)-1-(3-bromo-2-fluorophenyl)ethan-1-amine (CAS 1212802-38-4)
- (3S,4R,5R,6S)-2-(butylamino)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 29352-40-7)
- N-(9-((2R,3R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)-2-phenoxyacetamide (CAS 121076-16-2)
- Liraglutide Impurity 25 (CAS CATO-C4X-199225)
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