N-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2,2-difluoroethyl}-N-nitroguanidine CAS 1823194-73-5
| CAS No. | 1823194-73-5 |
| Molecular Formula | C9H7ClF5N5O2 |
| Molecular Weight | 347.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), N-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2,2-difluoroethyl}-N-nitroguanidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies N-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2,2-difluoroethyl}-N-nitroguanidine (CAS 1823194-73-5), a certified reference material (molecular formula C9H7ClF5N5O2, MW 347.63 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2,2-difluoroethyl}-N-nitroguanidine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 347.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H7ClF5N5O2 |
| Molecular Weight | 347.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related N Standards
- (3-Chloro-4-((3,4-dichlorobenzyl)oxy)-5-methoxyphenyl)methanol (CAS 676333-37-2)
- 2-((8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)thio)-2,2-difluoroacetic acid (CAS 1823184-08-2)
- 5-Chloro-7-iodo-8-isopropoxyquinoline (CAS 106920-05-2)
- 2-Chloro-7-cyclopentyl-6-iodo-7H-pyrrolo[2,3-d]pyrimidine (CAS 1383481-58-0)
- 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid (CAS 477886-68-3)
- 4-Chloro-7-cyclopentyl-5-iodopyrrolo[2,3-d]pyrimidine (CAS 213745-17-6)
- Ethyl 4-chloro-1-(3,5-dichlorophenyl)-6-oxo-1,6-dihydro-3-pyridazinecarboxylate (CAS 339030-94-3)
- N-(4-chloro-2-(trifluoromethyl)phenyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxamide (CAS 861208-52-8)
Recommended Standards
- 4-Bromo-3-(ethylsulfonyl)benzenesulfonyl chloride (CAS 1354954-42-9)
- 3-(Benzyloxy)-1-bromo-8-chloronaphthalene (CAS 2770350-54-2)
- 4-(1-Bromoethyl)-6-[(4-chlorophenyl)thio]-5-fluoropyrimidine (CAS 1112937-26-4)
- 6-Benzyloxy-2-bromo-5-chloronaphthalene (CAS 887343-51-3)
- 1-(Furan-2-ylmethyl)-3-(1-(hydroxymethyl)cyclopentyl)urea (CAS 1384595-91-8)
- (1S,4S)-4-Hydroxycyclopent-2-en-1-yl butyrate (CAS 625445-16-1)
- trans-1-(Bromoethyl)-4-pentylcyclohexane (CAS 71458-14-5)
- 4-Propylcyclohex-1-enylboronic acid (CAS 1256346-34-5)
- 1-(3-Nitrophenyl)-3-tosylpropan-1-one (CAS 477334-54-6)
- (R)-4-((S)-1-Fluoroethyl)oxazolidin-2-one (CAS 1628810-07-0)
- tert-Butyl (8-benzyl-8-azabicyclo[3.2.1]octan-3-yl)carbamate (CAS 287114-24-3)
- 2-Amino-N-(3-(trifluoromethyl)phenyl)acetamide hydrochloride (CAS 936447-60-8)
- (5H-[1,3]Dioxolo[4,5-f]indol-7-yl)boronic acid (CAS 948593-79-1)
- Semaglutide Impurity 3 (CAS CATO-C4X-22263)
Why CATO?
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