1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid CAS 477886-68-3
| CAS No. | 477886-68-3 |
| Molecular Formula | C13H9ClF3N3O3 |
| Molecular Weight | 347.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 347.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid (CAS 477886-68-3), a certified reference material (molecular formula C13H9ClF3N3O3, MW 347.68 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H9ClF3N3O3 |
| Molecular Weight | 347.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related chloro Standards
- N-(4-chloro-2-(trifluoromethyl)phenyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxamide (CAS 861208-52-8)
- 2-(4-Chloro-2-methylphenoxy)-N-(2,4-difluorophenyl)-2,2-difluoroacetamide (CAS 339104-68-6)
- 2-(4-Chloro-2-methylphenoxy)-N-(2,6-difluorophenyl)-2,2-difluoroacetamide (CAS 339010-97-8)
- N-(4-((7-chloro-4-nitrobenzo[c][1,2,5]oxadiazol-5-yl)amino)phenyl)acetamide (CAS 375837-77-7)
- 2-((8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)thio)-2,2-difluoroacetic acid (CAS 1823184-08-2)
- Ethyl 1-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-3-methyl-1H-pyrazole-5-carboxylate (CAS 1351479-11-2)
- (2Z)-3-[(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)amino]-2-cyanobut-2-enamide (CAS 303152-91-2)
- 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)-3-cyanopropan-2-yl cyclopropanecarboxylate (CAS 339016-29-4)
Recommended Standards
- 1-(2-(4-Bromo-2-chloro-3-methylphenoxy)ethyl)-4-methylpiperazine (CAS 2172820-44-7)
- N-(3,5-bis(trifluoromethyl)phenyl)-3-chloro-2,2-dimethylpropanamide (CAS 478261-82-4)
- N-(tert-Butyl)-N-chloro-3,5-bis(trifluoromethyl)benzamide (CAS 1845745-04-1)
- 1-(2-(4-Bromo-2-chlorophenoxy)ethyl)-4-ethylpiperazine (CAS 1704074-28-1)
- 2-Azaspiro[3.3]heptane-6-carboxylic acid (CAS 1172691-93-8)
- N*1*-(2-Chloro-thiazol-5-ylmethyl)-N*1*-isopropyl-ethane-1,2-diamine (CAS 1353980-05-8)
- 2-(Tributylstannyl)-5-chloropyridine 611168-63-9 C17H30ClNSn Y9613 (CAS 611168-63-9)
- 2,2',3,4,4',5',6-Heptabromodiphenyl Ether (CAS 207122-16-5)
- 6-Chloro-2-(4-fluorophenyl)-8-methylimidazo[1,2-b]pyridazine (CAS 1228217-15-9)
- sec-Butyl 4-amino-2-hydroxybenzoate (CAS 102338-91-0)
- 1-[(1,4-Diazepan-1-yl)methyl]cyclobutan-1-ol (CAS 2098500-79-7)
- 4-Methylpyrazole-3-carboxylic Acid (CAS 82231-51-4)
- Potassium (2-bromothiazol-5-yl)trifluoroborate (CAS 1150654-69-5)
- Semaglutide impurity 42 (CAS CATO-C4X-222642)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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