2-Chloro-5-(trifluoromethyl)phenylboronic Acid CAS 182344-18-9
| CAS No. | 182344-18-9 |
| Molecular Formula | C7H5BClF3O2 |
| Molecular Weight | 224.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-5-(trifluoromethyl)phenylboronic Acid (C7H5BClF3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-Chloro-5-(trifluoromethyl)phenylboronic Acid (CAS 182344-18-9) is a high-purity analytical reference standard with the molecular formula C7H5BClF3O2 and a molecular weight of 224.37 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-5-(trifluoromethyl)phenylboronic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5BClF3O2 |
| Molecular Weight | 224.37 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-Chloro-5-(trifluoromethyl)phenylboronic Acid (CAS 1160561-31-8)
- 5-Chloro-2-(trifluoromethyl)phenylboronic Acid (CAS 1195945-67-5)
- (3-Chloro-2-(trifluoromethyl)phenyl)boronic acid (CAS 1401990-62-2)
- 4-Chloro-3-(trifluoromethyl)phenylboronic Acid (CAS 176976-42-4)
- 2-Chloro-3-(trifluoromethyl)phenylboronic Acid (CAS 957061-11-9)
- 2-Chloro-4-(trifluoromethyl)phenylboronic Acid (CAS 254993-59-4)
- 2-Chloro-6-(trifluoromethyl)phenylboronic Acid (CAS 851756-52-0)
- 3-Chloro-4-(trifluoromethyl)phenylboronic Acid (CAS 847756-88-1)
Recommended Standards
- 3-Pentyl-4-(trimethylsilyl)cyclobut-3-ene-1,2-dione (CAS 181126-38-5)
- ((3AR,7aS)-2,2-dimethyl-3a,7a-dihydrobenzo[d][1,3]dioxol-5-yl)trimethylsilane (CAS 1998128-14-5)
- n-Methyl-1-(1-((5-methylthiophen-2-yl)methyl)pyrrolidin-3-yl)methanamine (CAS 1808547-85-4)
- (R)-N1,N1-dimethyl-4-(phenylthio)butane-1,3-diamine (CAS 870812-32-1)
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- 4-[(3-Nitro-2-pyridinyl)amino]butanoic acid (CAS 339101-31-4)
- 4-(4-Fluorobenzyl)-1-methyl-1H-pyrazole (CAS 2484889-16-7)
- (4-Cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl)proline (CAS 1092840-97-5)
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- 4-(methylamino)-2H-chromen-2-one (CAS 21315-45-7)
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Why CATO?
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