2-Chloro-4-(trifluoromethyl)phenylboronic Acid CAS 254993-59-4
| CAS No. | 254993-59-4 |
| Molecular Formula | C7H5BClF3O2 |
| Molecular Weight | 224.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Chloro-4-(trifluoromethyl)phenylboronic Acid (CAS 254993-59-4), a certified reference material (molecular formula C7H5BClF3O2, MW 224.37 g/mol) for analytical method development and quality control.
The molecular framework of 2-Chloro-4-(trifluoromethyl)phenylboronic Acid (C7H5BClF3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-4-(trifluoromethyl)phenylboronic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5BClF3O2 |
| Molecular Weight | 224.37 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-Chloro-5-(trifluoromethyl)phenylboronic Acid (CAS 1160561-31-8)
- 5-Chloro-2-(trifluoromethyl)phenylboronic Acid (CAS 1195945-67-5)
- (3-Chloro-2-(trifluoromethyl)phenyl)boronic acid (CAS 1401990-62-2)
- 4-Chloro-3-(trifluoromethyl)phenylboronic Acid (CAS 176976-42-4)
- 2-Chloro-5-(trifluoromethyl)phenylboronic Acid (CAS 182344-18-9)
- 2-Chloro-3-(trifluoromethyl)phenylboronic Acid (CAS 957061-11-9)
- 2-Chloro-6-(trifluoromethyl)phenylboronic Acid (CAS 851756-52-0)
- 3-Chloro-4-(trifluoromethyl)phenylboronic Acid (CAS 847756-88-1)
Recommended Standards
- 2,6-Dimethyldithieno[3,2-b:2',3'-d]thiophene (CAS 533930-12-0)
- 2-(Azepan-1-yl)-2-(thiophen-3-yl)ethan-1-amine (CAS 953894-17-2)
- 4-Chloro-2-(trifluoromethyl)phenylboronic Acid (CAS 313545-41-4)
- 2-(4-Methylpiperidin-1-yl)-2-(thiophen-2-yl)ethan-1-amine (CAS 791079-98-6)
- Bromopride (CAS 4093-35-0)
- 1-[(3-Chlorophenyl)methyl]-2-oxo-6-phenyl-1,2-dihydropyridine-3-carbonitrile (CAS 339108-94-0)
- 2-(2,4,5,7-Tetrahydropyrano[3,4-c]pyrazol-4-yl)acetic acid (CAS 1391733-68-8)
- 2-(4-Methylphenyl)-4,5-dihydro-1h-imidazole (CAS 13623-58-0)
- 5-Chloro-2-ethynyl-4-methoxypyrimidine (CAS 1330044-02-4)
- (2R,3S)-1-(tert-Butoxycarbonyl)-2-methylpiperidine-3-carboxylic acid (CAS 1932193-81-1)
- ethyl 2-hydroxy-2-(4-methanesulfonylphenyl)propanoate (CAS 1275811-23-8)
- Plomestane (CAS 77016-85-4)
- 3-(2-Methyl-1,3-thiazol-4-yl)propan-1-amine (CAS 1000538-65-7)
- Neuropeptide Y (13-36) (porcine) (CAS 113662-54-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com