3-Bromo-5-chloro-4-(trifluoromethyl)pyridin-2-amine CAS 1823953-79-2
| CAS No. | 1823953-79-2 |
| Molecular Formula | C6H3BrClF3N2 |
| Molecular Weight | 275.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 275.45 g/mol gives 3-Bromo-5-chloro-4-(trifluoromethyl)pyridin-2-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Bromo-5-chloro-4-(trifluoromethyl)pyridin-2-amine (CAS 1823953-79-2), molecular formula C6H3BrClF3N2 and molecular weight 275.45 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-Bromo-5-chloro-4-(trifluoromethyl)pyridin-2-amine (C6H3BrClF3N2) contains a nitrile group, fluorine/chlorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 275.45 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H3BrClF3N2 |
| Molecular Weight | 275.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 4-Bromo-1-[chloro(difluoro)-methoxy]-2-fluoro-benzene (CAS 105529-59-7)
- 1-Bromo-4-chloro-5-(difluoromethoxy)-2-fluoro-benzene (CAS 1108189-13-4)
- 2-Bromo-4-chloro-5-(trifluoromethyl)phenol (CAS 1203898-21-8)
- 2-Bromo-4-chloro-1-(trifluoromethoxy)benzene (CAS 1260810-00-1)
- 5-Bromo-6-chloro-4-trifluoromethyl-pyridin-2-ylamine (CAS 1311279-26-1)
- 1-Bromo-4-chloro-2-(trifluoromethoxy)benzene (CAS 1402672-86-9)
- 4-Bromo-6-chloro-2-trifluoromethylphenol (CAS 1414870-65-7)
- 1-Bromo-2-[chloro(difluoro)-methoxy]-4-fluoro-benzene 1417566-64-3 (CAS 1417566-64-3)
Recommended Standards
- 2-Bromo-6-chloro-5-(trifluoromethyl)pyridin-3-amine (CAS 1823865-96-8)
- 3-bromo-2-chloro-5-(trifluoromethyl)phenol (CAS 1881328-60-4)
- 5-Bromo-3-chloro-4-(trifluoromethyl)pyridin-2-amine (CAS 1823338-31-3)
- 5-Bromo-4-chloro-2-methyl-6-(trifluoromethyl)pyrimidine (CAS 1934616-93-9)
- 3,5-Dimethyloctan-4-one (CAS 7335-17-3)
- (1,4-Dioxaspiro[4.4]Nonan-2-yl)methanamine (CAS 4745-17-9)
- (2S, 5R)-5-Hydroxy-Pipecolic Acid (CAS 50439-45-7)
- 1-(Quinolin-8-yl)ethan-1-ol (CAS 73038-00-3)
- Palbociclib Impurity 55 (CAS 1430196-98-7)
- 4-Chloro-5-hydroxy-2-isopropylpyridazin-3(2H)-one (CAS 64178-62-7)
- Tetra-n-butylammonium iodotetrachloride (CAS 15625-59-9)
- N,2-dimethyl-4,5,6,7-tetrahydro-1,3-benzothiazole-4-carboxamide (CAS 95203-31-9)
- 2-Bromo-5-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide (CAS 1804845-91-7)
- [5-31]-Semaglutide (CAS CATO-C4X-2226263)
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