2'-Chloro-4'-methyl-5'H-spiro[cyclobutane-1,6'-thieno[2,3-d]pyrimidine] CAS 1823957-18-1
| CAS No. | 1823957-18-1 |
| Molecular Formula | C10H11ClN2S |
| Molecular Weight | 226.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2'-Chloro-4'-methyl-5'H-spiro[cyclobutane-1,6'-thieno[2,3-d]pyrimidine] is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2'-Chloro-4'-methyl-5'H-spiro[cyclobutane-1,6'-thieno[2,3-d]pyrimidine] (CAS 1823957-18-1), molecular formula C10H11ClN2S and molecular weight 226.73 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C10H11ClN2S, 2'-Chloro-4'-methyl-5'H-spiro[cyclobutane-1,6'-thieno[2,3-d]pyrimidine] contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 226.73 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2'-Chloro-4'-methyl-5'H-spiro[cyclobutane-1,6'-thieno[2,3-d]pyrimidine] meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11ClN2S |
| Molecular Weight | 226.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-Chloro-2-ethyl-5,6-dimethylthieno[2,3-d]pyrimidine (CAS 1019449-63-8)
- 2-Chloro-6-([(2-aminoethyl)sulfanyl]-methyl)benzonitrile (CAS 1147093-49-9)
- 4-Chloro-N-((dimethylamino)methylene)benzothioamide (CAS 138472-03-4)
- 2'-Chloro-4'-methyl-7'H-spiro[cyclobutane-1,6'-thieno[3,2-d]pyrimidine] (CAS 1422354-58-2)
- 4-Chloro-5-isobutylthieno[2,3-d]pyrimidine (CAS 1707562-98-8)
- 5-Chloro-1-isopropyl-1,3-dihydro-2H-benzo[d]imidazole-2-thione (CAS 175276-96-7)
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- N-(3-Chloro-2-methylphenyl)-4,5-dihydro-1,3-thiazol-2-amine (CAS 36318-59-9)
Recommended Standards
- 1-((6-Chloropyridin-3-yl)methyl)pyrrolidine-2-thione (CAS 230617-77-3)
- 1-(4-Amino-2-chlorophenyl)pyrrolidine-2-thione (CAS 640288-02-4)
- 2-Butyl-4-chlorothieno[2,3-d]pyrimidine (CAS 1503001-22-6)
- 1-Allyl-3-(4-chlorophenyl)thiourea (CAS 14255-79-9)
- (3-(Pyrazin-2-yl)-5-(trifluoromethyl)phenyl)boronic acid (CAS 2225180-54-9)
- N-(4-ethoxyphenyl)-1-(2,2,2-trifluoroethyl)piperidin-4-amine (CAS 1157474-18-4)
- 3-(3-Chloro-2-fluorophenyl)-4,5-dihydroisoxazole-5-carboxylic acid (CAS 1422386-61-5)
- Tizanidine Impurity 65 (CAS 67357-54-4)
- (3-Chloro-5-fluoro-2-hydroxyphenyl)(cyclopropyl)methanone (CAS 1251197-50-8)
- (S)-8-(trifluoromethyl)chroman-4-amine hydrochloride (CAS 1392219-36-1)
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