N-(1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide CAS 182495-81-4
| CAS No. | 182495-81-4 |
| Molecular Formula | C17H18FN3O5 |
| Molecular Weight | 363.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
N-(1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide (CAS 182495-81-4), molecular formula C17H18FN3O5 and molecular weight 363.34 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, N-(1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide (C17H18FN3O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 363.34 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), N-(1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H18FN3O5 |
| Molecular Weight | 363.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- 2,4-Diphenyl-6-(3,4,5-trifluorophenyl)-1,3,5-triazine (CAS 1808158-43-1)
- 2-(2-((6-(4-Fluorophenyl)pyridazin-3-yl)oxy)ethyl)isoindoline-1,3-dione (CAS 2097937-36-3)
- Benzyl 7-fluoro-2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylate (CAS 1797376-37-4)
- 4-((6,7-Dihydroxyisoquinolin-1-yl)methyl)-2,3-dihydroxybenzenesulfonic acid (CAS 66719-09-3)
- 2,2-Dichloroacetamide (CAS 683-72-7)
- Sibutramine Impurity H (CAS 59242-93-2)
- Amlodipine Mesylate (CAS 246852-12-0)
- N-(4-Cyclopropoxy-2-isopropoxyphenyl)methanesulfonamide (CAS 1243396-84-0)
- (2R,3S,5S)-5-(4-Amino-7H-imidazo[4,5-d][1,2,3]triazin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 34536-05-5)
- 1170296-25-9 4-{[2-(4-Fluorophenyl)pyrimidin-4-yl]oxy}benzoic acid MFCD14281618 (CAS 1170296-25-9)
- 4-Fluoro-2-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)benzonitrile (CAS 2629323-19-7)
- 3-Chloro-5,6,7,8-tetrahydrocinnoline (CAS 32078-92-5)
- Omega 6 Standard (CAS CATO-CCFD200519)
- D-Ala35-Tirzepatide (CAS CATO-CPTD788904)
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