5-Amino-2-fluoropyridine CAS 1827-27-6
| CAS No. | 1827-27-6 |
| Molecular Formula | C5H5FN2 |
| Molecular Weight | 112.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-Amino-2-fluoropyridine (CAS 1827-27-6), a certified reference material (molecular formula C5H5FN2, MW 112.11 g/mol) for analytical method development and quality control.
Owing to a nitrile group, fluorine substitution, 5-Amino-2-fluoropyridine is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 112.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H5FN2 |
| Molecular Weight | 112.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 2-Amino-6-fluoropyridine (CAS 1597-32-6)
- 4-Amino-2-fluoropyridine (CAS 18614-51-2)
- 2-Amino-4-fluoropyridine (CAS 944401-77-8)
- 2-Amino-3-fluoropyridine (CAS 21717-95-3)
- 2-Amino-5-fluoropyridine (CAS 21717-96-4)
- 4-Amino-1,3,5-triazin-2-ol (CAS 1118000-83-1)
- 3-Amino-2,5-dihydro-1,2,4-triazin-5-one (CAS 1121-90-0)
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Recommended Standards
- 5-Fluoro-4-methylpyrimidine (CAS 1785532-82-2)
- 2-Fluoro-5-methylpyrazine (CAS 1220799-57-4)
- 2-Fluoro-5-methylpyrimidine (CAS 62802-36-2)
- 4-Fluoropyridin-3-amine (CAS 1060804-19-4)
- 2-(Allyloxy)-3-chloropyridine (CAS 1365271-80-2)
- 1'H-Spiro[piperidine-4,4'-quinazolin]-2'(3'H)-one hydrochloride (CAS 885610-09-3)
- (S)-2-(((9H-FLuoren-9-yl)methoxy)carbonylamino)-6-(2-nitrophenylsulfonamido)hexanoic acid (CAS 359780-63-5)
- (3R,4S)-4-Aminopiperidin-3-ol (CAS 1388089-28-8)
- 3-[6-(1-Acetyl-piperidin-3-yl)-2-methyl-pyrimidin-4-yl]-propionic acid (CAS 1316221-68-7)
- 2-[2-(trifluoromethyl)phenoxymethyl]oxirane (CAS 4698-95-7)
- N,N-Dicarboxymethyl-N,N-dinitroso-p-phenylenediamine, disodium salt (CAS 1042969-16-3)
- N-(4-ethoxyphenyl)-1-(2,2,2-trifluoroethyl)piperidin-4-amine (CAS 1157474-18-4)
- Carbocisteine Impurity 41 (CAS CATO-C4X-201041)
- a-Bag Cell Peptide (1-8) (CAS 87549-53-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com