1-Cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-8-ethoxy-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid CAS 182868-75-3
| CAS No. | 182868-75-3 |
| Molecular Formula | C21H26FN3O4 |
| Molecular Weight | 403.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-Cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-8-ethoxy-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-Cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-8-ethoxy-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 182868-75-3), molecular formula C21H26FN3O4 and molecular weight 403.45 g/mol, is a CATO reference standard with documented purity and traceability.
1-Cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-8-ethoxy-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (C21H26FN3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H26FN3O4 |
| Molecular Weight | 403.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Cyclopropyl Standards
- 1-Cyclopropyl-6-fluoro-8-methoxy-7-((R)-3-((S)-1-(methylamino)ethyl)pyrrolidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 143383-65-7)
- Methyl 1-cyclopropyl-6-fluoro-8-methoxy-7-[3-(methylamino)piperidin-1-yl]-4-oxoquinoline-3-carboxylate (CAS 1820717-27-8)
- 1-Cyclopropyl-8-ethoxy-6-fluoro-7-(3-((methylamino)methyl)pyrrolidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 182868-80-0)
- 1-Cyclopropyl-8-ethoxy-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 182868-82-2)
- N-(3-Cyclopropyl-1-(6-oxo-4-phenyl-1,6-dihydropyrimidin-2-yl)-1H-pyrazol-5-yl)thiophene-2-carboxamide (CAS 1330155-76-4)
- Methyl 5-cyclopropyl-2-(4-fluorophenyl)-6-(methylsulfonamido)benzofuran-3-carboxylate (CAS 1416438-14-6)
- 1-Cyclopropyl-6,8-difluoro-7-((4aS,7aS)-1-methylhexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 151213-35-3)
- 2-(3-Cyclopropyl-4-(difluoromethyl)-6-(3,4-dimethoxyphenyl)-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 937607-35-7)
Recommended Standards
- 3-tert-butyl 5-propan-2-yl 7-fluoro-4,4-dimethyl-4H,5H-imidazo[1,5-a]quinoxaline-3,5-dicarboxylate (CAS 180990-12-9)
- (2S,4R)-Methyl 1-benzoyl-4-(tosyloxy)-pyrrolidine-2-carboxylate (CAS 31560-21-1)
- Methyl (2Z)-3-[(2H-1,3-benzodioxol-5-yl)amino]-2-[4-(propan-2-yl)benzenesulfonyl]prop-2-enoate (CAS 1327178-76-6)
- (Z)-[(4-Fluorophenyl)[2-(4-methylphenyl)cyclopropyl]methylidene]amino 4-methoxybenzoate (CAS 338749-03-4)
- 4-Bromo-3-phenyl-1h-pyrazole-5-carboxylic acid (CAS 1238384-46-7)
- 4-Ethyl-3,5-dimethyl-1H-pyrazole-1-carbonyl chloride (CAS 67514-67-4)
- 4-(3,5-Dimethylisoxazol-4-yl)benzaldehyde (CAS 630392-25-5)
- Erlotinib Impurity 75 (CAS CATO-C4X-106975)
- 3-Amino-7-hydroxy-2-methyl-4H-chromen-4-one (CAS 742008-52-2)
- N-octadecylformamide (CAS 32585-06-1)
- 2,4,6-trimethylbenzoyl isothiocyanate (CAS 32709-74-3)
- 9,10-Anthracenedione, 1,4-bis[(4-butylphenyl)amino]-5,8-dihydroxy- (CAS 28198-05-2)
- 3-(2-iodoethyl)indolin-2-one (CAS 2919523-96-7)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
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