1-Cyclopropyl-8-ethoxy-6-fluoro-7-(3-((methylamino)methyl)pyrrolidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid CAS 182868-80-0
| CAS No. | 182868-80-0 |
| Molecular Formula | C21H26FN3O4 |
| Molecular Weight | 403.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-Cyclopropyl-8-ethoxy-6-fluoro-7-(3-((methylamino)methyl)pyrrolidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 182868-80-0) is a high-purity analytical reference standard with the molecular formula C21H26FN3O4 and a molecular weight of 403.45 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1-Cyclopropyl-8-ethoxy-6-fluoro-7-(3-((methylamino)methyl)pyrrolidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 403.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H26FN3O4 |
| Molecular Weight | 403.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Cyclopropyl Standards
- 1-Cyclopropyl-6-fluoro-8-methoxy-7-((R)-3-((S)-1-(methylamino)ethyl)pyrrolidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 143383-65-7)
- Methyl 1-cyclopropyl-6-fluoro-8-methoxy-7-[3-(methylamino)piperidin-1-yl]-4-oxoquinoline-3-carboxylate (CAS 1820717-27-8)
- 1-Cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-8-ethoxy-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 182868-75-3)
- 1-Cyclopropyl-8-ethoxy-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 182868-82-2)
- N-(3-Cyclopropyl-1-(6-oxo-4-phenyl-1,6-dihydropyrimidin-2-yl)-1H-pyrazol-5-yl)thiophene-2-carboxamide (CAS 1330155-76-4)
- Methyl 5-cyclopropyl-2-(4-fluorophenyl)-6-(methylsulfonamido)benzofuran-3-carboxylate (CAS 1416438-14-6)
- 1-Cyclopropyl-6,8-difluoro-7-((4aS,7aS)-1-methylhexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 151213-35-3)
- 2-(3-Cyclopropyl-4-(difluoromethyl)-6-(3,4-dimethoxyphenyl)-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 937607-35-7)
Recommended Standards
- (2S,4R)-Methyl 1-benzoyl-4-(tosyloxy)-pyrrolidine-2-carboxylate (CAS 31560-21-1)
- 3-tert-butyl 5-propan-2-yl 7-fluoro-4,4-dimethyl-4H,5H-imidazo[1,5-a]quinoxaline-3,5-dicarboxylate (CAS 180990-12-9)
- (Z)-[(4-Fluorophenyl)[2-(4-methylphenyl)cyclopropyl]methylidene]amino 4-methoxybenzoate (CAS 338749-03-4)
- 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-phenylpiperidine-4-carboxylic acid (CAS 793727-36-3)
- 5-(tert-Butyl)-4-cyclopropoxy-2-methylpyridine (CAS 1243411-34-8)
- 3-((Benzyloxy)methyl)-4-isopropyl-1-(4-(trifluoromethyl)phenyl)-1H-1,2,4-triazol-5(4H)-one (CAS 1050441-88-7)
- 1-(3,3-Difluorocyclobutyl)piperazine (CAS 2020056-51-1)
- 4H,5H,6H-cyclopenta[c]furan-1-carboxylic acid (CAS 1596746-91-6)
- 5-Ethyl-N,N,4-trimethyl-4H-1,2,4-triazol-3-amine (CAS 733698-87-8)
- N-(2-(naphthalen-2-yloxy)ethyl)acetamide (CAS 883805-28-5)
- 4-(4-Methylphenyl)-3-{1-[4-(trifluoromethyl)benzoyl]piperidin-4-yl}-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775519-41-9)
- 3-(Aminomethyl)-1H-indazole (CAS 806640-37-9)
- 3-Amino-3-(2,3-difluorophenyl)propanoic acid (CAS 682804-04-2)
- Semaglutide impurity 275 (CAS CATO-C4X-2226275)
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