6-Chlorochroman-4-ol CAS 18385-76-7
| CAS No. | 18385-76-7 |
| Molecular Formula | C9H9ClO2 |
| Molecular Weight | 184.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chlorochroman-4-ol.
6-Chlorochroman-4-ol (CAS 18385-76-7), molecular formula C9H9ClO2 and molecular weight 184.62 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C9H9ClO2, 6-Chlorochroman-4-ol contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 184.62 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H9ClO2 |
| Molecular Weight | 184.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
Related Chlorochroman Standards
- 8-Chlorochroman-7-ol (CAS 1256255-23-8)
- (R)-6-chlorochroman-4-ol (CAS 1270284-06-4)
- 5-Chlorochroman-4-ol (CAS 1270585-45-9)
- 7-Chlorochroman-4-ol (CAS 18385-81-4)
- (R)-6-Chlorochroman-4-amine (CAS 1018978-86-3)
- (R)-7-chlorochroman-4-amine (CAS 1057246-81-7)
- (S)-7-chlorochroman-4-amine (CAS 1213320-82-1)
- (S)-8-Chlorochroman-4-amine (CAS 1228542-35-5)
Recommended Standards
- 2-Amino-3-chloro-N-methylbenzamide (CAS 18343-42-5)
- 4-Chloro-6-(tetrahydrofuran-2-yl)pyrimidine (CAS 1823913-80-9)
- 2-Chloro-4-(tetrahydrofuran-2-yl)pyrimidine (CAS 1850883-75-8)
- 2-(Dimethylamino)nicotinoyl chloride (CAS 181132-78-5)
- (S)-2-((S)-2-Acetamido-3-(1H-indol-3-yl)propanamido)-4-methylpentanamide (CAS 65356-77-6)
- 4-(Furan-2-yl)-3-methylbenzoic acid (CAS 1261960-66-0)
- 4-(2-Bromophenyl)-1-cyclopropyl-2-methyl-1H-imidazol-5-amine (CAS 1269530-71-3)
- 2-Amino-5-bromoquinazoline (CAS 181871-83-0)
- N-(4-Methoxyphenyl)-2-{N-[3-(trifluoromethyl)phenyl]4-chlorobenzenesulfonamido}acetamide (CAS 337922-19-7)
- Methyl Pyrophosphate (CAS 56399-35-0)
- (3S,4R)-1-(tert-butyl)-4-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid (CAS 782482-57-9)
- Boc-NH-PEG1-CH2COOH (CAS 142929-49-5)
- 1-(Spiro[2.2]pentan-1-yl)ethan-1-one (CAS 249563-62-0)
- 3X Flag Peptide trifluoroacetate salt (CAS 402750-12-3)
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