9-(2-Bromo-4-chlorophenyl)-9H-carbazole CAS 1838683-77-4
| CAS No. | 1838683-77-4 |
| Molecular Formula | C18H11BrClN |
| Molecular Weight | 356.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
9-(2-Bromo-4-chlorophenyl)-9H-carbazole (CAS 1838683-77-4) is a high-purity analytical reference standard with the molecular formula C18H11BrClN and a molecular weight of 356.64 g/mol.
The molecular framework of 9-(2-Bromo-4-chlorophenyl)-9H-carbazole (C18H11BrClN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 9-(2-Bromo-4-chlorophenyl)-9H-carbazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H11BrClN |
| Molecular Weight | 356.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
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- 9-(2-Bromo-3-chlorophenyl)-9H-carbazole (CAS 2126841-70-9)
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Recommended Standards
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- 2-Chloro-3-(difluoromethyl)-5-iodo-4-methylpyridine (CAS 1805385-02-7)
- 2-(1-Methyl-1H-imidazol-5-yl)ethan-1-ol (CAS 802027-25-4)
- Hexapeptide-9 (CAS 1228371-11-6)
- 2-Benzyl-5-nitro-1H-benzimidazole (CAS 7189-72-2)
- Benzylpenicillin Impurity 29 (CAS 58678-43-6)
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