Triclopyr impurity B CAS CATO-CCPD103605
| CAS No. | CATO-CCPD103605 |
| Molecular Formula | C13H16Cl3NO4 |
| Molecular Weight | 356.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Triclopyr impurity B (C13H16Cl3NO4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Triclopyr impurity B (CAS CATO-CCPD103605), a pharmacopoeial impurity reference standard (molecular formula C13H16Cl3NO4, MW 356.63 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H16Cl3NO4 |
| Molecular Weight | 356.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Triclopyr Standards
Recommended Standards
- 2-Chloro-9-(3,4-dichlorobenzyl)-N,N-dimethyl-9H-purin-6-amine (CAS 115204-65-4)
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- 9-(2-Bromo-5-chlorophenyl)-9H-carbazole (CAS 1361956-35-5)
- Diazepam Impurity 9 (CAS 17247-17-5)
- Ampicillin Impurity 49 (CAS CATO-C4X-144349)
- Ambroxol Impurity 26 (CAS CATO-C4X-108526)
- FCN437 Impurity 3 (CAS CATO-C4X-33243)
- 5-Formyl-3-methoxyphenylboronic acid (CAS 1451392-09-8)
- (2-Iodo-6-methylpyridin-4-yl)methanamine (CAS 1393533-43-1)
- Ethyl 6-bromo-3-chloro-5-ethylpyrazine-2-carboxylate (CAS 2168316-00-3)
- 4-(difluoromethoxy)-2-fluoro-5-nitroaniline (CAS 1803611-06-4)
- 9-Cyclopropylanthracene (CAS 26979-34-0)
- Phenol, 4,4'-(1-methylethylidene)bis-, polymer with 2,2'-[(1-methylethylidene)bis[4,1-phenyleneoxy[1-(butoxymethyl)-2,1-ethanediyl]oxymethylene]]bis[oxirane] (CAS 110553-33-8)
- Semaglutide impurity 205 (CAS CATO-C4X-2226205)
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