N-(2-(3-aminopiperidin-1-yl)-2-oxoethyl)-4-(trifluoromethyl)benzamide CAS 1839700-01-4
| CAS No. | 1839700-01-4 |
| Molecular Formula | C15H18F3N3O2 |
| Molecular Weight | 329.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(2-(3-aminopiperidin-1-yl)-2-oxoethyl)-4-(trifluoromethyl)benzamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-(2-(3-aminopiperidin-1-yl)-2-oxoethyl)-4-(trifluoromethyl)benzamide (CAS 1839700-01-4), molecular formula C15H18F3N3O2 and molecular weight 329.32 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(2-(3-aminopiperidin-1-yl)-2-oxoethyl)-4-(trifluoromethyl)benzamide (C15H18F3N3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(2-(3-aminopiperidin-1-yl)-2-oxoethyl)-4-(trifluoromethyl)benzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H18F3N3O2 |
| Molecular Weight | 329.32 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- (4-Aminopiperidin-1-yl)(3-iodophenyl)methanone (CAS 1579094-51-1)
- (4-Aminopiperidin-1-yl)(2-iodophenyl)methanone (CAS 1584989-68-3)
- 8-(4-Aminopiperidin-1-yl)-2-benzyl-[1,2,4]triazolo[4,3-a]pyrazin-3(2H)-one (CAS 1713713-94-0)
- 2-(2-(4-Aminopiperidin-1-yl)-2-phenylethoxy)benzonitrile (CAS 1227269-43-3)
- 8-(4-Aminopiperidin-1-yl)-2-(4-fluorobenzyl)-[1,2,4]triazolo[4,3-a]pyrazin-3(2H)-one (CAS 1713590-27-2)
- (4-Aminopiperidin-1-yl)(1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)methanone (CAS 1351788-71-0)
- (4-Aminopiperidin-1-yl)(1-(3-chlorophenyl)-1H-1,2,3-triazol-4-yl)methanone (CAS 1351837-83-6)
- (4-Aminopiperidin-1-yl)(3-(3-chlorophenyl)-1H-pyrazol-5-yl)methanone (CAS 1595511-79-7)
Recommended Standards
- 1-(4-Fluorophenyl)-7,7-dimethyl-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylic acid (CAS 1134334-88-5)
- 1-(4-((4-Fluorobenzyl)oxy)phenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 676479-42-8)
- 1,1,1-Trifluoro-3-(4-(3-(furan-2-yl)-1H-pyrazol-5-yl)piperidin-1-yl)propan-2-ol (CAS 1030937-45-1)
- 1-(Naphthalen-2-yl)-3-((2,3,4-trifluorophenyl)amino)propan-1-one (CAS 868255-61-2)
- 5-Cyclopropoxy-3-nitropicolinaldehyde (CAS 1243323-94-5)
- Terizidone (CAS 25683-71-0)
- 5-Methyl-2H-pyrrol-2-one (CAS 922179-95-1)
- (2E)-3-(2-Chloro-6-fluorophenyl)-1-(4-ethoxyphenyl)prop-2-en-1-one (CAS 1354941-19-7)
- 1-Isopropyl-1h-pyrazole-4-carbonyl chloride (CAS 1103424-89-0)
- (6-Chloro-2-(pyrrolidin-1-yl)pyrimidin-4-yl)boronic acid (CAS 1310404-65-9)
- 3-Methyl-5-(1H-pyrrol-1-yl)isoxazole (CAS 610311-52-9)
- Dimethyl(prop-2-yn-1-ylimino)-l6-sulfanone (CAS 1934471-26-7)
- ((3-Formyl-1H-indol-4-yl)thio)methyl acetate (CAS 113461-97-5)
- [Nva12]-Tirzepatide (CAS CATO-C4X-324042)
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