1-(Naphthalen-2-yl)-3-((2,3,4-trifluorophenyl)amino)propan-1-one CAS 868255-61-2

Purity 97%+In StockPharmaceutical Standards
CAS No.868255-61-2
Molecular FormulaC19H14F3NO
Molecular Weight329.32 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(Naphthalen-2-yl)-3-((2,3,4-trifluorophenyl)amino)propan-1-one CAS 868255-61-2 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

1-(Naphthalen-2-yl)-3-((2,3,4-trifluorophenyl)amino)propan-1-one (CAS 868255-61-2) is a high-purity analytical reference standard with the molecular formula C19H14F3NO and a molecular weight of 329.32 g/mol.

The molecular framework of 1-(Naphthalen-2-yl)-3-((2,3,4-trifluorophenyl)amino)propan-1-one (C19H14F3NO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

CATO manufactures 1-(Naphthalen-2-yl)-3-((2,3,4-trifluorophenyl)amino)propan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC19H14F3NO
Molecular Weight329.32 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing
Nitrogen Atoms1

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