1-(6-Chloro-1h-indol-3-yl)ethan-1-one CAS 184151-47-1
| CAS No. | 184151-47-1 |
| Molecular Formula | C10H8ClNO |
| Molecular Weight | 193.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(6-Chloro-1h-indol-3-yl)ethan-1-one (CAS 184151-47-1), molecular formula C10H8ClNO and molecular weight 193.63 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 1-(6-Chloro-1h-indol-3-yl)ethan-1-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 193.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 1-(6-Chloro-1h-indol-3-yl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8ClNO |
| Molecular Weight | 193.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
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- 6-Bromo-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole (CAS 1907643-13-3)
- (6-((4-Chlorophenyl)amino)pyridin-3-yl)boronic acid (CAS 951771-31-6)
- 4,6-Dimethyl-3-(4-methylbenzenesulfonyl)-2-[(4-methylphenyl)sulfanyl]pyridine (CAS 478245-43-1)
- Brucine (CAS 357-57-3)
- 3-(Dimethylamino)-2-(thiophene-2-carbonyl)acrylonitrile (CAS 52200-22-3)
- 2-Methylimidazo[2,1-b]thiazole (CAS 45667-45-6)
- 4-((1-Benzylpiperidin-4-yl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid (CAS 1033194-54-5)
- Sorafenib Impurity 15 (CAS CATO-C4X-112415)
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