N-(2,4-Difluorophenyl)-6-nitro-4-quinazolinamine CAS 184360-66-5
| CAS No. | 184360-66-5 |
| Molecular Formula | C14H8F2N4O2 |
| Molecular Weight | 302.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, N-(2,4-Difluorophenyl)-6-nitro-4-quinazolinamine (C14H8F2N4O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 302.24 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies N-(2,4-Difluorophenyl)-6-nitro-4-quinazolinamine (CAS 184360-66-5), a certified reference material (molecular formula C14H8F2N4O2, MW 302.24 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(2,4-Difluorophenyl)-6-nitro-4-quinazolinamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H8F2N4O2 |
| Molecular Weight | 302.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related N Standards
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- N-(3,4-difluorophenyl)-6-nitroquinazolin-4-amine (CAS 184360-64-3)
- 2-(3-(2,6-Difluorophenyl)-1,2,4-oxadiazol-5-yl)benzoic acid (CAS 1707584-70-0)
- 1-(2,4-Difluorophenyl)-3-(4-fluorophenyl)-1H-pyrazole-4-carbaldehyde (CAS 618098-78-5)
- 3-(5-(2,4-Difluorophenyl)-1,2,4-oxadiazol-3-yl)benzoic acid (CAS 775304-39-7)
- 3-(5-(2,6-Difluorophenyl)-1,2,4-oxadiazol-3-yl)benzoic acid (CAS 775304-19-3)
- N4-(2,4-Difluorophenyl)-N2-(3-hydroxypropyl)-L-asparagine (CAS 1048011-89-7)
Recommended Standards
- (4-Methoxy-3-nitrophenyl)(3-nitrophenyl)methanone (CAS 811836-23-4)
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- (Z)-4,6-Dihydroxy-2-(3,4,5-trihydroxybenzylidene)benzofuran-3(2H)-one (CAS 3260-50-2)
- 2-(3,4-Dihydroxyphenyl)-5,6,7-trihydroxy-4H-chromen-4-one (CAS 18003-33-3)
- 7-Methoxy-3,4-dihydrospiro[1-benzopyran-2,4'-piperidine]-4-one (CAS 927978-50-5)
- 2-(6-Methyl-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid (CAS 62214-19-1)
- 3-(4-(2-Methoxyphenyl)piperazin-1-yl)propanoic acid (CAS 732298-45-2)
- 4,7-Dimethoxy-1-methyl-1h-indole-2-carboxylic acid (CAS 858752-95-1)
- Methyl (2E,4E)-4-(benzenesulfonyl)-5-[(4-fluorophenyl)amino]penta-2,4-dienoate (CAS 339276-74-3)
- 1,2,2-Trimethylcyclopentan-1-ol (CAS 1121-95-5)
- Bis(4-ethoxyphenyl)amine (CAS 3949-80-2)
- Ethyl 3-((pyridin-4-ylmethyl)amino)propanoate (CAS 131436-67-4)
- Capecitabine EP Impurity G (CAS 162204-20-8)
- Semaglutide impurity 77 (CAS CATO-C4X-222677)
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