4-(3-chloro-4-fluorophenylamino)-6-Acetoxy -7-methoxyquinazoline Hydrochloride CAS 184475-70-5
| CAS No. | 184475-70-5 |
| Molecular Formula | C17H13ClFN3O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4-(3-chloro-4-fluorophenylamino)-6-Acetoxy -7-methoxyquinazoline Hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
4-(3-chloro-4-fluorophenylamino)-6-Acetoxy -7-methoxyquinazoline Hydrochloride (CAS 184475-70-5), molecular formula C17H13ClFN3O3HCl and molecular weight 398.21 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 4-(3-chloro-4-fluorophenylamino)-6-Acetoxy -7-methoxyquinazoline Hydrochloride is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 398.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C17H13ClFN3O3 HCl |
| Molecular Weight | 398.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- Ethyl 5-(4-methoxyphenyl)-2,7-dimethyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 324543-13-7)
- 2-(3-(Tert-butyl)phenyl)ethan-1-ol (CAS 935863-65-3)
- 4-((1H-tetrazol-5-yl)methyl)phenol (CAS 119192-12-0)
- Levothyroxine Impurity 17 (CAS 51-26-3)
- Ethyl 3-(3,5-diamino-4-hydroxyphenyl)propanoate (CAS 199180-07-9)
- N2-acetyl-N6-diazo-L-lysine (CAS 1505525-07-4)
- 2-(4-(Oxetan-3-yl)phenyl)acetic acid (CAS 1547059-04-0)
- Racemic Solifenacin Succinate (CAS 180272-14-4)
- 5-(Bromomethyl)benzofuran (CAS 188862-35-3)
- Palmitoyl Tripeptide-5 TFA (CAS 623172-55-4（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com