Methyl 3-(((tert-butyldimethylsilyl)oxy)methyl)cyclobutane-1-carboxylate CAS 1848239-63-3
| CAS No. | 1848239-63-3 |
| Molecular Formula | C13H26O3Si |
| Molecular Weight | 258.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Methyl 3-(((tert-butyldimethylsilyl)oxy)methyl)cyclobutane-1-carboxylate (C13H26O3Si) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Methyl 3-(((tert-butyldimethylsilyl)oxy)methyl)cyclobutane-1-carboxylate (CAS 1848239-63-3), a certified reference material (molecular formula C13H26O3Si, MW 258.43 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H26O3Si |
| Molecular Weight | 258.43 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1995 |
Recommended Standards
- Dimethoxydi(piperidin-1-yl)silane (CAS 180536-06-5)
- (1R,4r)-4-((tert-butyldimethylsilyl)oxy)cyclohexane-1-carboxylic acid (CAS 955401-29-3)
- (2-(7-Oxabicyclo[4.1.0]heptan-3-yl)ethyl)diethoxy(methyl)silane (CAS 14857-35-3)
- 2-{4-[(tert-butyldimethylsilyl)oxy]oxan-4-yl}acetaldehyde (CAS 2060024-66-8)
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