Cimetidine Impurity 21 CAS 182685-55-8

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.182685-55-8
Molecular FormulaC16H26N10S2
Molecular Weight422.57 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Cimetidine Impurity 21 CAS 182685-55-8 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Cimetidine Impurity 21 (CAS 182685-55-8) is a certified pharmaceutical impurity reference standard with the molecular formula C16H26N10S2 and a molecular weight of 422.57 g/mol.

The molecular framework of Cimetidine Impurity 21 (C16H26N10S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC16H26N10S2
Molecular Weight422.57 g/mol
Purity>95%
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2009
Nitrogen Atoms10
Sulfur Atoms2

Related Cimetidine Standards

Recommended Standards

Why CATO?