4-(Difluoromethyl)-2-methylthiazole CAS 1849218-92-3
| CAS No. | 1849218-92-3 |
| Molecular Formula | C5H5F2NS |
| Molecular Weight | 149.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 4-(Difluoromethyl)-2-methylthiazole (CAS 1849218-92-3), a certified reference material (molecular formula C5H5F2NS, MW 149.16 g/mol) for analytical method development and quality control.
Structurally, 4-(Difluoromethyl)-2-methylthiazole (C5H5F2NS) contains a nitrile group, sulfur-containing functionality, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 149.16 g/mol, it falls into the low-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H5F2NS |
| Molecular Weight | 149.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Difluoromethyl Standards
- 5-(Difluoromethyl)-4-methylthiazole (CAS 1965305-15-0)
- 4-(Difluoromethyl)thiophen-3-amine (CAS 2002442-01-3)
- 4-(Difluoromethyl)cyclohexanamine (CAS 1314939-44-0)
- 1-(Difluoromethyl)cyclohexan-1-amine (CAS 1461704-88-0)
- 3-(Difluoromethyl)cyclohexanamine (CAS 1461714-07-7)
- 3-(Difluoromethyl)-3-methylpiperidine (CAS 1780516-15-5)
- 2-(difluoromethyl)-3,5-dimethyl-1H-pyrrole (CAS 2756415-03-7)
- 2-(Difluoromethyl)-4-Methyl-1,3-Oxazol-5(2H)-One (CAS 154140-57-5)
Recommended Standards
- 3-Fluoro-2,4-dimethylbenzonitrile (CAS 1806330-91-5)
- 5-Ethynyl-4-fluoro-2-methylaniline (CAS 1849222-66-7)
- 6-(fluoromethyl)-1,4-oxazepan-6-ol (CAS 1801455-04-8)
- (4-Ethynyl-3-fluorophenyl)methanamine (CAS 1849373-43-8)
- 4-Hydroxy-7-phenoxyisobenzofuran-1,3-dione (CAS 89450-88-4)
- 2-(Difluoromethyl)-4-hydroxy-5-nitropyridine-3-acetonitrile (CAS 1805393-86-5)
- 2-cyclopropyl-1-phenylpropan-2-ol (CAS 95101-94-3)
- (2S,4S)-1-(tert-Butoxycarbonyl)-4-(2-methoxy-4-methylphenoxy)-2-pyrrolidinecarboxylic acid (CAS 1354486-73-9)
- Adrenaline Impurity 47 (CAS CATO-C4X-184947)
- Ethylalanine (CAS 64991-30-6)
- 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-methylbutanoyl chloride (CAS 64404-11-1)
- (2-(1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)phenyl)methanamine (CAS 910095-35-1)
- 5-(3-Quinolinyl)-2-thiophenecarboxylic acid (CAS 893738-34-6)
- MLCK inhibitor peptide 18 (CAS 224579-74-2)
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