5-(Difluoromethyl)-4-methylthiazole CAS 1965305-15-0
| CAS No. | 1965305-15-0 |
| Molecular Formula | C5H5F2NS |
| Molecular Weight | 149.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-(Difluoromethyl)-4-methylthiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-(Difluoromethyl)-4-methylthiazole (CAS 1965305-15-0) is a high-purity analytical reference standard with the molecular formula C5H5F2NS and a molecular weight of 149.16 g/mol.
Owing to a nitrile group, sulfur-containing functionality, fluorine substitution, 5-(Difluoromethyl)-4-methylthiazole is typically white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 149.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H5F2NS |
| Molecular Weight | 149.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Difluoromethyl Standards
- 4-(Difluoromethyl)-2-methylthiazole (CAS 1849218-92-3)
- 4-(Difluoromethyl)thiophen-3-amine (CAS 2002442-01-3)
- 4-(Difluoromethyl)cyclohexanamine (CAS 1314939-44-0)
- 1-(Difluoromethyl)cyclohexan-1-amine (CAS 1461704-88-0)
- 3-(Difluoromethyl)cyclohexanamine (CAS 1461714-07-7)
- 3-(Difluoromethyl)-3-methylpiperidine (CAS 1780516-15-5)
- 2-(difluoromethyl)-3,5-dimethyl-1H-pyrrole (CAS 2756415-03-7)
- 2-(Difluoromethyl)-4-Methyl-1,3-Oxazol-5(2H)-One (CAS 154140-57-5)
Recommended Standards
- 5-fluoro-2-methoxy-pyridin-4-ol (CAS 1883698-71-2)
- ((2S,4S,5S)-5-Amino-4-fluorotetrahydro-2H-pyran-2-yl)methanol (CAS 2642377-55-5)
- (4-Ethynyl-2-fluorophenyl)methanamine (CAS 1866305-46-5)
- (S)-2-Amino-4-fluoro-4-methylpentanoic Acid (CAS 857026-04-1)
- 2-(4-((2-Nitrophenyl)sulfonyl)piperazin-1-yl)pyrimidine (CAS 545358-46-1)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(cyclopropyl)methanone (CAS 898762-46-4)
- 2-(Di-tert-butylphosphino)-N,N,N-trimethylethanaminium chloride (CAS 360577-23-7)
- 1-(2,4,6-Trimethylbenzyl)piperazine (CAS 41717-26-4)
- tert-Butyl 4-((4-chloro-5-methylpyrimidin-2-yl)oxy)piperidine-1-carboxylate (CAS 1261232-25-0)
- 5-Chloro-2-fluorophenylacetic Acid (CAS 261762-97-4)
- (3-Amino-5-bromophenyl)methanol (CAS 954124-45-9)
- 5-Cyclopropyl-1-methyl-1H-pyrazole-3-carbonitrile (CAS 1177227-87-0)
- 2-(4-(Difluoromethyl)-5-iodo-2-methylpyridin-3-yl)acetic acid (CAS 1806857-53-3)
- Peptide 439 (CAS CATO-CPTD788439)
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