N-Nitroso Pseudoephedrine (N-Nitroso Ephedrine HCl EP Impurity B) CAS 1850-88-0
| CAS No. | 1850-88-0 |
| Molecular Formula | C10H14N2O2 |
| Molecular Weight | 194.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
N-Nitroso Pseudoephedrine (N-Nitroso Ephedrine HCl EP Impurity B) (CAS 1850-88-0) is a certified pharmaceutical impurity reference standard with the molecular formula C10H14N2O2 and a molecular weight of 194.23 g/mol.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, N-Nitroso Pseudoephedrine (N-Nitroso Ephedrine HCl EP Impurity B) is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 194.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), N-Nitroso Pseudoephedrine (N-Nitroso Ephedrine HCl EP Impurity B) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14N2O2 |
| Molecular Weight | 194.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related N Standards
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Recommended Standards
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- Betamethasone Impurity 76 (CAS 5534-01-0)
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- 2-(4-Bromo-1-methyl-1h-pyrazol-5-yl)ethanamine (CAS 1017788-72-5)
- 2-Methoxypyridine-3-carboxamide (CAS 7145-28-0)
- (E)-2-Bromo-3-phenylacrylaldehyde (CAS 99686-39-2)
- 4-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)benzohydrazide (CAS 870766-48-6)
- 103244-41-3 Insulin-like Growth Factor-II fragment 33-40 Ser-Arg-Val-Ser-Arg-Arg-Ser-Arg (CAS 103244-41-3)
Why CATO?
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