1-Chloro-3-ethynyl-2-(trifluoromethyl)benzene CAS 1851097-56-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1851097-56-7
Molecular FormulaC9H4ClF3
Molecular Weight204.58 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-Chloro-3-ethynyl-2-(trifluoromethyl)benzene CAS 1851097-56-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Chloro-3-ethynyl-2-(trifluoromethyl)benzene.

CATO supplies 1-Chloro-3-ethynyl-2-(trifluoromethyl)benzene (CAS 1851097-56-7), a certified reference material (molecular formula C9H4ClF3, MW 204.58 g/mol) for analytical method development and quality control.

The molecular framework of 1-Chloro-3-ethynyl-2-(trifluoromethyl)benzene (C9H4ClF3) is characterized by fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC9H4ClF3
Molecular Weight204.58 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Cl-containing

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