1-(4-Chlorophenyl)-3,3,3-trifluoropropyne CAS 82203-84-7
| CAS No. | 82203-84-7 |
| Molecular Formula | C9H4ClF3 |
| Molecular Weight | 204.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(4-Chlorophenyl)-3,3,3-trifluoropropyne (C9H4ClF3) is characterized by fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-(4-Chlorophenyl)-3,3,3-trifluoropropyne (CAS 82203-84-7) is a high-purity analytical reference standard with the molecular formula C9H4ClF3 and a molecular weight of 204.58 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(4-Chlorophenyl)-3,3,3-trifluoropropyne meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H4ClF3 |
| Molecular Weight | 204.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | F/Cl-containing |
Related Chlorophenyl Standards
- 3-(4-Chlorophenyl)-1,1-difluoropropan-2-one (CAS 1179782-41-2)
- 5-(4-Chlorophenyl)isoxazole-3-carbonitrile (CAS 1173252-25-9)
- 2-((4-Chlorophenyl)(hydroxy)methylene)malononitrile (CAS 5593-28-2)
- 2-(3-Chlorophenyl)-2H-1,2,3-triazole-4-carbonitrile (CAS 1263215-33-3)
- 5-(2-Chlorophenyl)-2H-1,2,3-triazole-4-carbonitrile (CAS 1352925-45-1)
- 5-(3-Chlorophenyl)-2H-1,2,3-triazole-4-carbonitrile (CAS 1352925-75-7)
- 4-(4-Chlorophenyl)-1H-1,2,3-triazole-5-carbonitrile (CAS 50710-06-0)
- 4-(3-Chlorophenyl)phenol (CAS 126485-57-2)
Recommended Standards
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- N-(4-methylbenzyl)-1-(pyridin-4-yl)methanamine (CAS 626210-31-9)
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