(R)-4-(1-(3-Chloro-2-methyl-2H-indazol-5-yl)-5-methyl-4-(3-(methylamino)piperidine-1-carbonyl)-1H-imidazol-2-yl)-2-fluorobenzonitrile CAS 1853269-07-4
| CAS No. | 1853269-07-4 |
| Molecular Formula | C26H25ClFN7O |
| Molecular Weight | 505.97 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-4-(1-(3-Chloro-2-methyl-2H-indazol-5-yl)-5-methyl-4-(3-(methylamino)piperidine-1-carbonyl)-1H-imidazol-2-yl)-2-fluorobenzonitrile.
CATO supplies (R)-4-(1-(3-Chloro-2-methyl-2H-indazol-5-yl)-5-methyl-4-(3-(methylamino)piperidine-1-carbonyl)-1H-imidazol-2-yl)-2-fluorobenzonitrile (CAS 1853269-07-4), a certified reference material (molecular formula C26H25ClFN7O, MW 505.97 g/mol) for analytical method development and quality control.
Based on its molecular formula C26H25ClFN7O, (R)-4-(1-(3-Chloro-2-methyl-2H-indazol-5-yl)-5-methyl-4-(3-(methylamino)piperidine-1-carbonyl)-1H-imidazol-2-yl)-2-fluorobenzonitrile contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 505.97 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H25ClFN7O |
| Molecular Weight | 505.97 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 7 |
Related R Standards
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Recommended Standards
- rel-(E)-N-(7-(((1R,5S,6s)-3-oxabicyclo[3.1.0]hexan-6-yl)ethynyl)-4-((3-chloro-4-fluorophenyl)amino)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide (CAS 1398833-56-1)
- 3-(((4-Chlorobenzyl)thio)methyl)-4-phenyl-5-((4-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazole (CAS 344269-28-9)
- 4,5-Bis(2,3,5-trichlorophenyl)-2-(trifluoromethyl)pyridine (CAS 1361717-76-1)
- Dexamethasone Impurity 84 (CAS CATO-C4X-116584)
- 1,3-Bis(5-methyl-3-phenylisoxazol-4-yl)urea (CAS 240799-55-7)
- 1-[5-Chloro-2-nitro-4-(trifluoromethyl)phenyl]azepane (CAS 646456-34-0)
- Taxifolin (CAS 480-18-2)
- 5-[(2-Chlorophenyl)sulfanyl]-N-(4-methoxyphenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 321553-40-6)
- (E)-3-(3-Fluoro-5-methoxyphenyl)acrylic acid (CAS 628732-18-3)
- Levothyroxine Impurity 18 (CAS 1155-40-4)
- 2-chloro-N-(2-methoxybenzyl)-N-methylacetamide (CAS 851175-19-4)
- 2-Dodecyltetradecanoic Acid (CAS 24251-98-7)
- 1-Acetyl-4-pyridin-3-ylmethyl-[1,4]diazepane-6-carboxylic acid (CAS 1316223-23-0)
- Cyclopeptide-5 (CAS 197172-76-2)
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