2-chloro-N-(2-methoxybenzyl)-N-methylacetamide CAS 851175-19-4
| CAS No. | 851175-19-4 |
| Molecular Formula | C11H14ClNO2 |
| Molecular Weight | 227.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-chloro-N-(2-methoxybenzyl)-N-methylacetamide (CAS 851175-19-4) is a high-purity analytical reference standard with the molecular formula C11H14ClNO2 and a molecular weight of 227.69 g/mol.
The molecular framework of 2-chloro-N-(2-methoxybenzyl)-N-methylacetamide (C11H14ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H14ClNO2 |
| Molecular Weight | 227.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related chloro Standards
- 2-Chloro-N-(4-isopropoxyphenyl)acetamide (CAS 100129-54-2)
- Ethyl 2-chloro-6-(propan-2-yl)pyridine-3-carboxylate (CAS 100129-72-4)
- 2-Chloro-N-[2-(dimethylamino)ethyl]nicotinamide (CAS 1016674-02-4)
- 4-Chloro-1-isobutyl-6-methyl-2-oxo-1,2-dihydropyridine-3-carbaldehyde (CAS 1018302-97-0)
- 4-((4-Chloro-6-methylpyrimidin-2-yl)methyl)morpholine (CAS 1023818-62-3)
- 6-Chloro-N2-cyclobutyl-N4-ethyl-1,3,5-triazine-2,4-diamine (CAS 102587-50-8)
- 1-(4-chloro-1H-pyrrole-2-carbonyl)-1,4-diazepane (CAS 1038213-92-1)
- Methyl 3-((3-chloro-4-methylphenyl)amino)propanoate (CAS 105909-47-5)
Recommended Standards
- tert-Butyl 4-amino-3-chlorobenzoate (CAS 934481-40-0)
- Telmisartan Impurity 10 (CAS 136304-93-3)
- tert-Butyl 4-Amino-2-chlorobenzoate (CAS 75294-49-4)
- Capivasertib Impurity 39 (CAS CATO-C4X-331239)
- 2-Chloro-5,6-dimethoxy-benzothiazole (CAS 864169-35-7)
- 2-(tert-Butyl)-4-iodoaniline (CAS 881057-14-3)
- Methyl 2-[(3-methoxy-3-oxopropyl)amino]-2-methylpropanoate (CAS 106556-64-3)
- Tryptophan EP Impurity E (CAS 3978-11-8)
- Tert-butyl 3-((cyclobutylamino)methyl)piperidine-1-carboxylate (CAS 887586-35-8)
- 4-Cyclopropoxy-6-isopropyl-N,N-dimethylnicotinamide (CAS 1243346-99-7)
- 4,4'-(1,2,4,5-Tetrazine-3,6-diyl)dibenzoic acid (CAS 753031-26-4)
- N2-Butyl-9H-purine-2,6-diamine (CAS 5463-09-2)
- 2-(2-Bromoethoxy)-1,3-dimethylbenzene (CAS 37136-92-8)
- (Tyr9)-Cholecystokinin Octapeptide (sulfated) (H-9770.0005) (CAS 96607-61-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com