4,5-Dihydroxy-1,3-bis(hydroxymethyl)imidazolidin-2-one CAS 1854-26-8
| CAS No. | 1854-26-8 |
| Molecular Formula | C5H10N2O5 |
| Molecular Weight | 178.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4,5-Dihydroxy-1,3-bis(hydroxymethyl)imidazolidin-2-one is closely related to a carbohydrate-derived structure, an amide group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4,5-Dihydroxy-1,3-bis(hydroxymethyl)imidazolidin-2-one (CAS 1854-26-8), a certified reference material (molecular formula C5H10N2O5, MW 178.14 g/mol) for analytical method development and quality control.
4,5-Dihydroxy-1,3-bis(hydroxymethyl)imidazolidin-2-one (C5H10N2O5) contains a carbohydrate-derived structure, an amide group. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H10N2O5 |
| Molecular Weight | 178.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Dihydroxy Standards
- 2,3-Dihydroxy-2,3-dimethylsuccinic acid (CAS 74543-88-7)
- 3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carboxylic acid (CAS 52993-96-1)
- 4,5-Dihydroxy-2H-chromen-2-one (CAS 30992-74-6)
- 5,7-Dihydroxy-2H-chromen-2-one (CAS 2732-18-5)
- (4S)-4,8-Dihydroxy-3,4-dihydronaphthalene-1(2H)-one (CAS 54712-38-8)
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Recommended Standards
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- 3-amino-N-butyl-N-phenylbenzene-1-sulfonamide (CAS 1489610-80-1)
- ethyl 2-(4-bromo-1h-pyraZol-1-yl)butanoate (CAS 1005650-19-0)
- 4-Piperidinylmethyl 2,2,2-trichloroacetatehydrochloride (CAS 1220020-55-2)
- Clopidogrel Impurity 42 (CAS 109904-36-1)
- 4’-tert-butyl-1,1’-biphenyl-3-amine hydrochloride (CAS 1171447-32-7)
- 2-Bromo-3,5-dinitrobenzoic acid (CAS 116529-60-3)
- Bis(4-(4-methoxyphenyl)piperazine-1-carboximidamide), sulfuric acid (CAS 1384428-70-9)
- Cyclohexyl(1H-pyrrolo[2,3-b]pyridin-6-yl)methanone (CAS 942261-72-5)
- Met(O)14-Exenatide trifluoroacetate salt (CAS 1678417-38-3)
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