1-(2,2-Difluoroethyl)-4-ethynyl-1H-pyrazole CAS 1855890-49-1
| CAS No. | 1855890-49-1 |
| Molecular Formula | C7H6F2N2 |
| Molecular Weight | 156.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(2,2-Difluoroethyl)-4-ethynyl-1H-pyrazole is closely related to a nitrile group, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(2,2-Difluoroethyl)-4-ethynyl-1H-pyrazole (CAS 1855890-49-1) is a high-purity analytical reference standard with the molecular formula C7H6F2N2 and a molecular weight of 156.13 g/mol.
1-(2,2-Difluoroethyl)-4-ethynyl-1H-pyrazole (C7H6F2N2) contains a nitrile group, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(2,2-Difluoroethyl)-4-ethynyl-1H-pyrazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6F2N2 |
| Molecular Weight | 156.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoroethyl Standards
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Recommended Standards
- 1-(Difluoromethyl)-4-ethynyl-5-methyl-1H-pyrazole (CAS 1855889-94-9)
- 1-Difluoromethyl-4-ethynyl-3-methyl-1h-pyrazole (CAS 1855899-98-7)
- 2,3-Difluoroacetophenone (CAS 18355-80-1)
- 2,5-Difluoroacetophenone (CAS 1979-36-8)
- N-(2-(2,2-dichloroacetamido)ethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 338404-73-2)
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- (1-(2-Methoxyphenyl)-1H-pyrazol-4-yl)methanamine (CAS 1177307-49-1)
- 3-(2-Ethoxyethyl)-1,2-oxazol-5-amine (CAS 1094310-65-2)
- Tau Peptide (245-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 1428134-39-7)
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