1-(2,2-Difluoroethyl)-3-((2,2,2-trifluoroethoxy)methyl)-1H-pyrazole CAS 1856025-55-2
| CAS No. | 1856025-55-2 |
| Molecular Formula | C8H9F5N2O |
| Molecular Weight | 244.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2,2-Difluoroethyl)-3-((2,2,2-trifluoroethoxy)methyl)-1H-pyrazole (CAS 1856025-55-2) is a high-purity analytical reference standard with the molecular formula C8H9F5N2O and a molecular weight of 244.16 g/mol.
Based on its molecular formula C8H9F5N2O, 1-(2,2-Difluoroethyl)-3-((2,2,2-trifluoroethoxy)methyl)-1H-pyrazole contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 244.16 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9F5N2O |
| Molecular Weight | 244.16 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoroethyl Standards
- 1-(2,2-Difluoroethyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid (CAS 1006462-23-2)
- 1-(2,2-Difluoroethyl)-3-methyl-1h-pyrazole-4-sulfonyl chloride (CAS 1006462-96-9)
- Methyl 4-(1,1-difluoroethyl)-2-nitrobenzoate (CAS 912575-27-0)
- (2,2-Difluoroethyl)({[4-methoxy-3-(methoxymethyl)phenyl]methyl})amine (CAS 1011396-69-2)
- (2,2-Difluoroethyl)[2-(3,4-dimethoxyphenyl)ethyl]amine (CAS 1182736-24-8)
- n-(2,2-Difluoroethyl)-1-(methylsulfonyl)piperidin-4-amine (CAS 1183768-67-3)
- 9-(1,1-Difluoroethyl)anthracene (CAS 1204295-73-7)
- 3-(1,1-Difluoroethyl)benzene-1-sulfonyl chloride (CAS 1597429-54-3)
Recommended Standards
- Diethyl P-[(ethoxyphosphinyl)methyl]phosphonate (CAS 179015-82-8)
- 1-(Difluoromethyl)-3-((3,3,3-trifluoropropoxy)methyl)-1H-pyrazole (CAS 1856074-57-1)
- 1-(2,5-Dichlorophenyl)cyclopentanemethanamine (CAS 1784038-08-9)
- 1-(3,5-Dichlorophenyl)cyclopentanemethanamine (CAS 1895831-04-5)
- 1-(Methoxymethoxy)-4-nitrobenzene (CAS 880-03-5)
- 4-(Difluoromethoxy)-3-fluoro-3'-(trifluoromethoxy)-1,1'-biphenyl (CAS 1261611-39-5)
- 1-[(Thiophen-3-yl)methyl]piperazine dihydrochloride (CAS 1211256-64-2)
- (2S,4S)-4-(difluoromethyl)-5-oxopyrrolidine-2-carboxylic acid (CAS 527705-01-7)
- Cabazitaxel Impurity 21 (CAS 132127-34-5)
- 8-Bromoisoquinoline 2-oxide (CAS 475994-58-2)
- 1,3,5-Trifluoro-2,4,6-tris(phenylethynyl)benzene (CAS 674289-04-4)
- 5-Bromo-3,4-dihydroisoquinolin-1(2H)-one (CAS 1109230-25-2)
- Benzoyl Ecgonine Isopropyl Ester (CAS 137819-55-7)
- Semaglutide Impurity 149 (CAS CATO-C4X-2226149)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com