(2S,4S)-4-(difluoromethyl)-5-oxopyrrolidine-2-carboxylic acid CAS 527705-01-7
| CAS No. | 527705-01-7 |
| Molecular Formula | C6H7F2NO3 |
| Molecular Weight | 179.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2S,4S)-4-(difluoromethyl)-5-oxopyrrolidine-2-carboxylic acid (CAS 527705-01-7) is a high-purity analytical reference standard with the molecular formula C6H7F2NO3 and a molecular weight of 179.12 g/mol.
Based on its molecular formula C6H7F2NO3, (2S,4S)-4-(difluoromethyl)-5-oxopyrrolidine-2-carboxylic acid contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 179.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (2S,4S)-4-(difluoromethyl)-5-oxopyrrolidine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H7F2NO3 |
| Molecular Weight | 179.12 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 4,4-Difluoro-1-methyl-5-oxopyrrolidine-3-carboxylic acid (CAS 1782418-67-0)
- (S)-Methyl 4,4-difluoro-5-oxopyrrolidine-2-carboxylate (CAS 333956-61-9)
- 1-(Difluoromethyl)-2-oxopyrrolidine-3-carboxylic acid (CAS 1586813-24-2)
- 2-(Difluoromethyl)-5-oxopyrrolidine-2-carboxylic acid (CAS 95755-28-5)
- N-(3-formyl-5-(trifluoromethyl)pyridin-2-yl)pivalamide (CAS 1261365-46-1)
- 2-((4-Allyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-bromo-2-methylphenyl)acetamide (CAS 575461-00-6)
- (S)-3,3-difluoropiperidin-4-ol hydrochloride (CAS 2375164-95-5)
- Methyl 3-carbamoyl-5-nitrobenzoate (CAS 50826-00-1)
- 6-Amino-2,3-difluorobenzenethiol (CAS 143163-90-0)
- 1-{2-[5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]thiophen-3-yl}-2,5-dimethyl-1H-pyrrole (CAS 672949-49-4)
- 3,4,5-Trimethoxy-N-(3-(7-methylimidazo[1,2-a]pyridin-2-yl)phenyl)benzamide (CAS 708995-11-3)
- 2-(3-Amino-4-bromo-1h-pyrazol-1-yl)-N-isopropyl-N-methylacetamide (CAS 1247402-64-7)
- 5-Nitroquinoxaline (CAS 18514-76-6)
- (Leu31,Pro34)-Peptide YY (human) trifluoroacetate salt (CAS 179986-95-9)
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